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Pharmaceuticals Market Reports

mTOR Inhibitors Therapeutics - Pipeline Analysis 2017, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

mTOR (mechanistic/mammalian target of rapamycin) plays an important role in the development and proliferation of the body cells and acts on protein kinase complexes, such as mTOR complex 1 and 2 (mTORC1/2). Rapamycin, the first inhibitor of mTOR, has been approved as an immunosuppressant, that blocks T-cell activation and has been in use since 2000 for the prevention of kidney graft rejection. Temsirolimus, a drug manufactured by Pfizer Inc., used for the treatment of advanced renal cell carcinoma has been approved by the... Continue Reading

Global Infectious Disease Treatment Market Size, Share, Development, Growth and Demand Forecast to 2023

Infectious diseases are medical conditions or disorders caused by microorganisms such as bacteria, fungi, viruses and other parasites. Several organisms are present in and on human bodies. Some organisms are normally harmless and even helpful. However, under certain circumstances, some organisms cause diseases. Infectious diseases spread from one person to another.  ... Continue Reading

Global Breast Cancer Market Size, Share, Development, Growth and Demand Forecast to 2023

Cancer is a disease characterized by uncontrolled growth of cell. There are about 100 different types of cancer and each is classified by the type of cell where it occurs and affects. Breast cancer is mostly prevalent in women, however, breast cancer in men is rare. It is frequently diagnosed in aged women and one of the leading causes of death among them. Some of the most  ... Continue Reading

Global Glaucoma Therapeutics Market Size, Share, Development, Growth and Demand Forecast to 2023

Glaucoma is a disease of eye which is caused by excessive increase of fluid pressure within the eye. Glaucoma is caused due to mechanical compression or decreased blood flow in the optic nerve of the patient’s eye. If not treated properly, it may lead to mild loss of vision and even blindness. Treatment of glaucoma includes laser therapies, pharmaceutical drugs and surgical  ... Continue Reading

Global Asthma Market Size, Share, Development, Growth and Demand Forecast to 2023

Asthma is a respiratory condition, where the airways become inflamed and narrow, which can cause a serious and incurable condition if left untreated. Breathlessness, wheezing and coughing are some of the symptoms of asthma and it can be controlled by avoiding triggers and with the help of drug therapy. Environmental triggers may vary from consumer to consumer but it can  ... Continue Reading

Global Choroidal Neovascularization (CNV) Market Size, Share, Development, Growth and Demand Forecast to 2023

Choroidal neovascular are the new blood vessels that grow just below the retina and interrupt the vision. Choroid, which is responsible for oxygen and nutrients supply to the eye, is the area between the retina and the sclera, where the blood vessels grow and cause choroidal neovascularization (CNV). Choroidal neovascularization break the barrier between retina and choroid  ... Continue Reading

Global Industry Insight: Human Insulin Market Development and Demand Forecast to 2020

The global human insulin market size is projected to reach $48.4 billion by 2020, growing at a CAGR of 12.5% during the forecast period. Some of the major factors driving the growth of the human insulin market are increasing aging population, increasing diabetic population and increasing prevalence of obesity. ... Continue Reading

Global Cytomegalovirus Retinitis Market Size, Share, Development, Growth and Demand Forecast to 2023

One of the major trends noticed in the cytomegalovirus retinitis market is usage of off-label drugs for the treatment of cytomegalovirus retinitis. Innovation of products focusing on better efficacy, growing demographics and growing economies in the developing countries, such as China and India, are some of the opportunities for global cytomegalovirus retinitis market.   ... Continue Reading

Global Restless Legs Syndrome Market Size, Share, Development, Growth and Demand Forecast to 2023

Restless legs syndrome increases at night when the patient is at rest. RLS are common in both, male and female; however the disease has its highest impact on woman who are elderly or in some cases woman with the age 35 to 50 years. Some of the most common symptoms of the restless legs syndrome are continue itching and pain in the legs, and unusual sleep pattern. The restless legs syndrome ... Continue Reading

Global Pompe Disease Market Size, Share, Development, Growth and Demand Forecast to 2023

Pompe disease is a type of lysergic acid diethylamide (LSD). LSD refers to a group of diseases arising from the increase of specific substrates and is inherited autosomal recessive disorders. Lysergic acid diethylamide is progressive and having uneven age of onset and clinical symptoms. Pompe disease is a hereditary and repeatedly incurable disorder caused by lack of acid  ... Continue Reading

Global Gastrointestinal Over the Counter (OTC) Drugs Market Size, Share, Development, Growth and Demand Forecast to 2023

Gastrointestinal diseases involve the gastrointestinal tract including stomach, esophagus, large intestine, small intestine, gallbladder, rectum, liver and pancreas. Over the counter (OTC) drugs are medications that are available without any prescription from the doctor. Over the counter drugs are chosen by regulatory agencies very carefully so as to ensure their efficacy and safety. ... Continue Reading

Global Opioid Induced Constipation Market Size, Share, Development, Growth and Demand Forecast to 2023

Opioids are directed to the patients suffering from the acute and chronic non-cancer pain. The opioids have numerous adverse intestinal effects, such as opioid-induced constipation. The opioids also affect the discharge of digestive enzymes that can sometime cause partial gastro paresis. Some of the most familiar symptoms of opioid-induced constipation includes, hard and dry  ... Continue Reading

Global Diabetic Retinopathy Market Size, Share, Development, Growth and Demand Forecast to 2023

Diabetic retinopathy refers to an eye disorder that damages or harms the blood vessels of the retina. Diabetic retinopathy can cause permanent blindness. Chronic diabetes is a major root of diabetic retinopathy. High glucose level in the blood can damage blood vessels in the retina. Diabetic retinopathy can also cause diabetic macular edema: a medical condition led to the leakage  ... Continue Reading

Global Uveitis Treatment Market Size, Share, Development, Growth and Demand Forecast to 2023

Globally, North America is the largest, while Asia-Pacific is the fastest growing uveitis treatment market. The uveitis treatment market is witnessing significant growth, due to increasing prevalence of uveitis and related complications. The global uveitis treatment market currently has many technologically innovative products in the pipeline, which are expected to improve efficiency  ... Continue Reading

Global Osteoporosis Drugs Market Size, Share, Development, Growth and Demand Forecast to 2022 – Industry Insights by Drug Class (Bisphosphonates, Parathyroid Hormone Therapy, Selective Estrogen Receptor Modulators, Rank Ligand Inhibitor, Calcitonin and Others)

The global osteoporosis drugs market was valued at an $8,835.4 million in 2015, and is expected to grow at a CAGR of 3.8% during 2016 – 2022, to reach $11,482.1 million by 2022. The market will be growing at a significant rate due to increasing healthcare expenditure and increasing awareness of osteoporotic care. ... Continue Reading

Global Diabetic Nephropathy Market Size, Share, Development, Growth and Demand Forecast to 2023

The increase in research and development funds for drug discovery followed by growing awareness of kidney-related disorders, and diabetes are the major factors driving the expansion of the global diabetic nephropathy market. Globally, many programs are organized by the American Diabetes Association to prevent diabetes, create awareness among vulnerable populations, and  ... Continue Reading

Global Active Pharmaceutical Ingredients Market Size, Share, Development, Growth and Demand Forecast to 2023

The global active pharmaceutical ingredient market is growing significantly due to patent expiry of biologic drugs in the industry. Patent expiry of blockbuster drugs has boosted the demand for low cost substitutes, which further increases the demand for active pharmaceutical ingredients in the industry. Moreover, increasing investment into biosimilars is expected to support the  ... Continue Reading

Global Nuclear Medicine (Radiopharmaceuticals) Market Size, Share, Development, Growth and Demand Forecast to 2023

The global nuclear medicine/radiopharmaceuticals market is growing significantly due to increasing prevalence of cancer and cardiovascular diseases, and advances in nuclear medicine imaging procedures. High demand of nuclear medicines in emerging economies and potential radiopharmaceuticals in the pipeline create ample opportunities for the nuclear  ... Continue Reading

Global Influenza Vaccine Market Size, Share, Development, Growth and Demand Forecast to 2023

The global influenza vaccine market is growing significantly due increasing awareness about the pandemic influenza viruses and increasing government involvement for vaccination against influenza viruses.Massive unexplored influenza vaccine marketin the emerging economiesare creating ample opportunities for the global influenza vaccine marketto grow at a significant  ... Continue Reading

Global Contraceptives Market Size, Share, Development, Growth and Demand Forecast to 2023

The global contraceptives market is growing significantly due to increasing incidences of unwanted pregnancies, increasing prevalence of sexually transmitted diseases and advances in contraception techniques. In addition, government and non-government organizations are funding and supporting programs to encourage contraception. Large unexplored contraceptives  ... Continue Reading

Global Autoimmune Treatment Market Size, Share, Development, Growth and Demand Forecast to 2023

The global autoimmune treatment market is growing significantly due to increasing incidences of autoimmune diseases, up surging healthcare expenditure, and advancements in the technologies for the development of autoimmune diseases therapeutics. Autoimmune diseases are chronic in nature and do not have permanent  ... Continue Reading

Anti-Obesity Drugs Market Size, Share, Development, Growth and Demand Forecast to 2023

The global anti-obesity drugs market is growing significantly, due to high prevalence of obesity and rich pipeline for anti-obesity drugs. The presence of large patient pool and massive unexplored market in the emerging economies, such as India and China, are creating ample opportunities for the growth of the global anti-obesity drugs market. The advanced research and development ... Continue Reading

Global Biopharmaceuticals Market Size, Share, Development, Growth and Demand Forecast to 2020 – Industry Insights by Type (Monoclonal Antibodies, Recombinant Proteins, Interferon, Colony-Stimulating Factor, Erythropoietin, Recombinant Human Insulin, Vaccines, Growth Hormones, Purified Proteins and others) and by Application (Oncology, Inflammatory and Infectious Diseases, Metabolic Disorders, Neurological Disorders, Cardiovascular Diseases and Others)

The global biopharmaceuticals market size is projected to reach $278.2 billion by 2020, growing at a CAGR of 9.6 during the forecast period. Increasing prevalence of chronic diseases, increasing R&D investment, growing aging population and technological advancements in biopharmaceuticals are the major growth drivers of the market. ... Continue Reading

Human Growth Hormone Market Size, Share, Development, Growth and Demand Forecast to 2023

The global human growth hormone market is witnessing growth due to the presence of large pool of patients and technological advancements. The increasing compliance for human growth hormone drugs and massive unexplored market in the emerging economies, such as India and China are creating opportunities for the growth of the global human growth hormone market. The  ... Continue Reading

Global Dermatology Drug Market Size, Share, Development, Growth and Demand Forecast to 2023

The increasing prevalence of skin diseases and growing aging population around the world are the predominant growth drivers for the global dermatology drug market. Acne, psoriasis, and dermatitis are some common skin diseases. Acne is the most common dermatological condition, which is caused by clogging of hair follicles by sebum, dirt, and dead skin cells. Acne affects  ... Continue Reading

Global Muscle Relaxant Drugs Market Size, Share, Development, Growth and Demand Forecast to 2020 – Industry Insights by Facial Aesthetic Relaxant Drug (Botox, Dysport, and Others), By Skeletal Muscle Relaxant Drug (Baclofen, Methocarbamol, Carisoprodol, Metaxalone, Tizanidine, and Others), and by Neuromuscular Blocking Agent (Non-depolarizing Agents, and Depolarizing Agents)

The global market of muscle relaxants is growing due to increase in geriatric population, increasing prevalence of skin diseases and harmful effects of ultra violet radiation. Old age is associated with the loss of fibrous tissue, and reduced vascular and glandular network in the layers of skin. In the elderly population, the appearance and characteristics of the skin gets altered,  ... Continue Reading

Global Pain Management Drugs Market Size, Share, Development, Growth and Demand Forecast to 2023

The growing geriatric population and increasing demand of innovative and advanced pain relaxing medications around the world are the predominant growth drivers for the global pain management drugs market. Additionally, the increasing number of hospitalization cases; unmet requirements for neuropathic pain management drugs; innovative and advanced applications of  ... Continue Reading

Global T-Cell Immunotherapy Pipeline Analysis, 2016 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

T-cell immunotherapy mainly consists of T-cell receptor (TCR), Tumor-infiltrating lymphocytes (TILs) and Chimeric antigen receptors (CAR) T-cell therapy. TCR is a complex integral membrane protein that activates T-cells in response to an antigen. ... Continue Reading

Protein A Resin Market Size, Share, Development, Growth and Demand Forecast to 2025

The global protein A resin market is expected to witness considerable growth during the forecast period due to the increasing research and development activities and increasing prevalence of chronic diseases. High traction for monoclonal antibodies in biopharmaceutical industry is supporting the growth of the global market. The increasing demand for monoclonal antibodies has fueled the need for high capacity commercial scale purification of monoclonal antibodies. Protein A resins are designed for the simple and rapid puri... Continue Reading

Global Age-Related Macular Degeneration (AMD) Market Size, Share, Development, Growth and Demand Forecast to 2022 – Industry Insights by Type (Dry AMD, and Wet AMD), by Drug (Lucentis, Eylea, Visudyne, Avastin and Others)

The global age-related macular degeneration (AMD) market size is predicted to reach $8.9 billion by 2022, growing at a CAGR of 7.6% during the forecast period. The growing geriatric population, increasing prevalence of AMD and increasing prevalence of lifestyle associated disease are driving the growth of the AMD industry. ... Continue Reading

Rectal Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Rectal cancer is a disease in which malignant (cancer) cells are formed in the tissues of the rectum. Rectal cancer usually develops over several years, first growing as a precancerous growth known as polyp. Some polyps can turn into cancer and begin to grow by its different stages. ... Continue Reading

Global Human Microbiome Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global human microbiome market is expected to witness significant growth due to increasing awareness towards healthy lifestyle, increasing demand for safe and effective medication, high number of patients with gastrointestinal diseases, inflammatory bowel diseases, obesity and cancer. The regulatory bodies are supporting the growth of market by providing designations and grants for speeding up the drug development process. Orphan drug designation and breakthrough therapy designation was given to RBX2660, a Rebiotix In... Continue Reading

Global Graft Versus Host Disease (GVHD) Treatment Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global graft versus host disease (GVHD) treatment market is expected to witness considerable growth due to increasing number of hematopoietic stem cell transplantations (HSCTs), advancement in technologies, and increasing collaboration among the pharmaceutical companies. The regulatory bodies are supporting the graft versus host disease market by providing designations and grants for speeding up the drug development process. ... Continue Reading

Global Mammalian Target of Rapamycin (mTOR) Inhibitors Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global mammalian target of rapamycin (mTOR) inhibitors market is witnessing considerable growth due to their application in several therapeutic areas such as cancer, renal dysfunction and eye disorders. The regulatory bodies are providing funding and designation to the drug candidates for advancement of their products. Moreover, the increasing awareness related to the effective use of mTOR inhibitors, in combination with chemotherapy and its implications  ... Continue Reading

Global Programmed Death-1 (PD-1) & Programmed Death Ligand-1 (PD-L1) Inhibitors Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2025 – Industry Insights by Drug (Opdivo, Keytruda, Tecentriq, Durvalumab, Avelumab), by Mechanism of Action (PD-1 Inhibitor, PD-L1 Inhibitor)

Programmed Death-1 (PD-1) and Programmed Death Ligand-1 (PD-L1) inhibitors are the therapeutic candidates or drugs, popularly known as checkpoint inhibitors, used most commonly for the treatment of cancer and other malignancies. Programmed death 1 (PD-1) is found on the surface of cancer cells and it is used by tumor cells to evade the immune system. PD-1 inhibitors  ... Continue Reading

Idiopathic Pulmonary Fibrosis (IPF) Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Idiopathic pulmonary fibrosis (IPF) is referred to as progressive and chronic interstitial pneumonia without known cause. Pulmonary fibrosis is a disease in which tissue profound in lungs becomes stiff and dense over time. The scar tissue formation is known as fibrosis. As the fibrosis progresses and tissue become darker, lungs can't properly move oxygen into the bloodstream, which result in oxygen deficiency in brain and other organs. ... Continue Reading

Global Natural Killer (NK) Cell Therapeutics Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global natural killer (NK) cell therapeutics market is expected to witness considerable growth due to increasing awareness regarding immunotherapy, advancement in technologies, high demand for safe and effective medication, reduction of side effects, high prevalence of chronic diseases such as cancer and cardiovascular diseases, and increasing incidences of infectious diseases. The regulatory bodies are supporting the growth of the global market ... Continue Reading

Global Antibody Drug Conjugates (ADCs) Therapeutics Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global antibody drug conjugates (ADCs) therapeutics market is expected to witness significant growth due to current unmet medical need of some chronic diseases such as cancer and immunological diseases, increasing prevalence of such diseases, advancement in technologies and high demand for safe and effective medication. The regulatory bodies are supporting the ADCs market by providing designations and funding for speeding up the drug ... Continue Reading

Global Ocular Pain Treatment Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global ocular pain treatment market is expected to witness considerable growth due to increasing awareness about the eye disorders, technological advancement in ocular therapeutic and diagnostic test, and increasing number of lifestyle related ocular diseases. In addition, increasing geriatric population and increasing disposable income are further supporting the growth of the global ocular pain market. ... Continue Reading

Global Personalized Medicine Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global personalized medicine market is expected to witness significant growth due rapid advancement in diagnostic techniques, population heterogeneity across the globe, increasing awareness about the benefits of genetic makeup based drugs, and improving quality of disease diagnosis. The key vendors in the global personalized medicine market are focusing on oncology, infectious disease and cardiovascular targeted treatment and diagnostics. ... Continue Reading

Global Chronic Pain Treatment Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global chronic pain treatment market is expected to witness considerable growth due to current unmet medical need of chronic pain, technological advancement in pain therapeutic and diagnostic test, and increasing number of chronic diseases such as cancer, arthritis, and diabetes mellitus. In addition, increasing geriatric population and increasing disposable income are supporting the growth of the global chronic pain market. The pharmaceutical ... Continue Reading

Global Immune Checkpoint Inhibitors Market - Pipeline Analysis, Market Size, Share, Development, Growth and Demand Forecast to 2023

The global immune checkpoint inhibitors market is expected to witness significant growth as these are proven to be more effective therapy in shrinking tumor in higher proportion of patients, as compared to other immunotherapies. Immune checkpoint inhibitors are applicable to a wider range of tumor types such as advanced or metastatic non-small cell lung cancer, renal cancer and melanoma. These inhibitors lower the rate of severe toxicities ... Continue Reading

Global BET Inhibitors Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Bromodomain and extra-terminal (BET) inhibitors are small molecule inhibitors including bromodomain 2 (BRD2), bromodomain 3 (BRD3), bromodomain 4 (BRD4) and bromodomain testis (BRDT), which have anti-proliferating properties. These targets of inhibitors are supposed to bind with myc gene, which is a most desired target for cancer therapeutics. BET inhibitors are first-in-class targeted therapies that directly target bromodomain proteins to deliver a new ... Continue Reading

Cyclin-Dependent Kinase (CDK) Inhibitors Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The hallmark of cancer is the continuous proliferative capacity of cancerous cells. In mammalian cells progression is controlled by the cell cycle, where checkpoints are regulated by CDKs. CDK 4 and CDK 6 regulates cell cycle progression at the G1 restriction point, thus are highly considered as anti-cancer drug targets. The cell cycle contains a dimeric enzyme which becomes active and inactive at regular intervals. The dimeric enzyme consists of a catalytic subunit, CDK and a regulatory subunit, cyclin. CDK with cyclin c... Continue Reading

AKT/Protein Kinase B (PKB) Inhibitors - Pipeline Analysis 2018

AKT, also known as Protein Kinase B (PKB), is overexpressed or activated in large number of human cancers, including breast, lung, gastric, ovary and pancreas. AKT inhibitor inhibits the activated form of AKT that leads to normal functioning of AKT kinases. AKT has three isoforms; AKT1, AKT2 and AKT3, which play an important role in regulation of diverse cellular functions such as metabolism, motility, cell survival, cell-cycle progression and transcription. ... Continue Reading

Estrogen Receptor-Positive Breast Cancer Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Estrogen Receptor-Positive (ER+) breast cancer is the most common type of breast cancer diagnosed and it refers to the cancer cells that have receptors on their surface to bind with estrogen. Breast cancer is said to be estrogen receptor-positive (ER+), if it contains estrogen that receives signals from estrogen to promote cell growth. Breast cancer is a syndrome that affects breast tissues and cells in the breast grow in an uncontrollable manner forming ... Continue Reading

Friedreich’s Ataxia (FRDA) Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Friedreich’s ataxia (FRDA) is an inherited autosomal recessive genetic condition that progressively damages the nervous system, affecting the people between 10 and 15 years of age. The risk factor of Friedreich's ataxia is diabetes mellitus and heart diseases including cardiomyopathy and cardiac arrhythmias. Friedreich's ataxia occurs due to mutation in the frataxin (FXN) gene, which is inherited from both parents, leading to the presence of mutations in both copies of FXN gene. The initial symptoms of Fried... Continue Reading

Fungal Infections - Pipeline Analysis 2018

Fungal Infection is a major cause of morbidity worldwide. Fungal Infections are caused by different fungi found in environment. Although, some fungi are not dangerous at all but few types of fungi are harmful to health. It involves the invasion of tissue such as skin and lung by specific type of fungi. According to Centers for Disease Control and Prevention (CDC), a public health institute in the U.S., approximately 1.5 million different species of fungi are present on ... Continue Reading

Hepcidin antagonist - Pipeline Analysis 2018

Hepcidin is a small peptide which acts as iron regulatory hormone. The name ‘hepcidin’ is taken from the place of synthesis in hepatocytes (hep), whereas cidin denotes its antimicrobial activity. Liver is the key organ that secrete hepcidin and regulates iron hormone. Hepcidin was initially observed in human urine sample and in human blood ultrafiltrate as a small bactericidal peptide (defensin and cathelicidin) and now it is known as liver–expressed ... Continue Reading

Interstitial Cystitis (IC) Disease - Pipeline Analysis 2018

Interstitial Cystitis (IC) is a painful bladder syndrome in which inflamed and irritated bladder cause recurring discomfort or pain. The symptoms of IC include an urgent or frequent need to urinate and pain during bladder filling. Women are more prone to develop this condition. Pain may be mild or so severe as to be debilitating and it can vary from day to day. IC is categorized into non-ulcerative and ulcerative. Non-ulcerative IC is the most common condition found in ... Continue Reading

Beta-Secretase (BACE) Inhibitors Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

BACE is a cleaving enzyme of aspartyl protease with beta-secretase activity. It acts as a precursor of beta-amyloid (Aβ) protein. In Alzheimer’s disease, the Aβ protein fragments get accumulated in plaques in the brain. BACE initiates Aβ production by cleaving amyloid precursor protein (APP) to generate APPβ and C99, which is critical for the subsequent cleavage of C99 by gamma-secretase to release Aβ1-40 and Aβ1-42. Inhibition of BACE enzyme disrupts the ... Continue Reading

Janus Kinase (JAK) Inhibitors - Pipeline Analysis 2018

Janus kinase (JAK) inhibitors block Janus kinase activator enzymes and interrupt signaling pathway. It plays an important role in host defense, oncology, autoimmunity and hematological cancers, which makes them an important target for therapeutics. Many signal transduction pathways are done by JAK activity for the normal signaling. The abnormal aberration in JAKs activity can lead to diseased state. For instance, over activation of JAK can lead to ... Continue Reading

Lysosomal Storage Disorder Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Lysosomal storage disorder refers to inherited metabolic disorders that are characterize by enzyme deficiencies, which results in an abnormal build-up of various toxic materials in the body's cells. There are nearly 50 types of lysosomal storage disorder which affect various parts of the body including the brain, skeleton, heart, central nervous system and skin. Some of the lysosomal storage disorders are Aspartylglucosaminuria, Batten Disease, Cystinosis, Fabry ... Continue Reading

Phosphatidylinositol 3-Kinase (PI3K) Inhibitors Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration and Other Developments

Phosphatidylinositol 3-kinases (PI3K) are lipid kinases that play a vital role in cell regulation, including cell survival, proliferation and differentiation. They act as intermediate molecules in PI3K/AKT/mTOR signaling pathway by sending chemical messengers from cell surface to cytoplasm. These signals activate multiple effector kinase pathways, including protein kinase B, bruton's tyrosine kinase and protein kinase C pathway, which result in survival and growth of normal cells. Recent cancer studies have shown that... Continue Reading

Rhinovirus Infection Therapeutics – Clinical Pipeline Development Analysis 2018

Rhinovirus is a small, non-enveloped, icosahedral virus having size of around 27 nm diameter. It contains one positive-strand RNA and belongs to Picornavirus family. Discovered in 1956, rhinovirus has over 100 antigenically distinct serotypes such as RhV A, RhV B groups, and RhV A2 and RhV C subclasses, based on their sequence similarity and cell entry receptors. Human rhinovirus is a positive-sense RNA virus of 7.2 kb single strand, having ... Continue Reading

Serine/Threonine-Protein Kinase Inhibitors - Pipeline Analysis 2018

Serine/threonine-protein kinases (EC 2.7.11.1) are enzyme or protein that has hydroxyl (OH) group in the side chain. Phosphorylation in serine or threonine residues may cause changes in the function of the target protein. Those drugs/ligands that inhibit phosphorylating activity of these kinases are called serine/threonine protein kinases inhibitors. Serine/threonine kinase receptors are a family of transmembrane receptors containing intracellular ... Continue Reading

Ulcerative Colitis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration and Other Developments

Ulcerative colitis is a chronic inflammatory disease, which basically affects colonic mucosa. The main identified symptoms of the disease are bloody diarrhea, abdominal cramps and fatigue. Some of the other symptoms include, fever, vomiting, anorexia, abdominal distension and bloating. The leading cause of ulcerative colitis is the imbalance in regulation of gastrointestinal immune system. According to the International Society for Pharmacoeconomic and Outcomes Research journal named as value in health, the prevalence of ... Continue Reading

Vasomotor Symptoms of Menopause Therapeutics - Pipeline Analysis 2018

Vasomotor symptoms occur when a woman reach the state of menopause and ovaries stop producing eggs, and there is a reduction in secretion of hormones such as estrogen and progesterone. It usually occurs naturally, most often between age of 45 years to 51 years. The women feel perimenopausal transition that generally occurs prior to cessation of menstruation. During perimenopausal transition, the menstruation cycle becomes ... Continue Reading

Chronic Obstructive Pulmonary Disease (COPD) Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Chronic obstructive pulmonary disease (COPD) is a broad term used for progression of various diseases affecting the lungs such as, chronic bronchitis, some forms of bronchiectasis, emphysema and refractory (non-reversible) asthma. Breathlessness and coughing are few of the early symptoms that induce the hypothesis of having COPD, but some people also consider these symptoms as the signs of aging. In no time, these ailments come under severe progression and reveal the rising of other associated diseases. The primary diagno... Continue Reading

Hyperhidrosis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designations, Collaborations, and Other Developments

Hyperhidrosis is a medical condition in which the eccrine glands are overactive and produce more sweat than normal to regulate normal body temperature. There are two types of hyperhidrosis namely primary focal hyperhidrosis and secondary (generalized) hyperhidrosis. Primary focal hyperhidrosis generally occurs at multiple locations on the body including axillary, palmar, plantar, trunk/inguinal, craniofacial and it often begins in childhood or adolescence age. Secondary (generalized) hyperhidrosis occur due to excessive s... Continue Reading

Japanese Encephalitis (JE) Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designations, Collaborations, and Other Developments

As of October 2017, the Japanese encephalitis therapeutics pipeline comprises of 12 drug candidates in different stages of development. ... Continue Reading

Alzheimer’s Disease Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Alzheimer’s disease is a progressive brain disorder that gradually destroys thinking skills and memory, and ultimately the capability to carry out the basic tasks. Alzheimer’s disease is presently ranked as the third leading cause of death in the aging population, after heart disease and cancer. Alzheimer’s is the most common form of dementia among elder adults. Dementia is the loss of behavioral abilities and cognitive functioning which results in interference with a person’s daily life and activi... Continue Reading

Global Acute Lymphoblastic Leukemia (ALL) Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

The global acute lymphoblastic leukemia therapeutics market is expected to witness considerable growth in the coming year since new drug formulations are proving to be the most effective treatment for cancer. An increasing awareness regarding cancer treatment, various technological advancements, high demand for safe and effective medications and high prevalence of cancer, are driving the growth of the global acute lymphoblastic leukemia therapeutics ... Continue Reading

Global Acute Myeloid Leukemia (AML) Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

The global acute myeloid leukemia therapeutics market is expected to witness notable growth, in the coming year due to increase in the new innovative and targeted drug delivery system. Various factors such as rising awareness regarding cancer treatments, increasing demand for safe and successful medications, rising incidence of cancer and technological advancements have been driving the growth of the global acute myeloid leukemia therapeutics ... Continue Reading

Global Chronic Lymphocytic Leukemia (CLL) Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

The global chronic lymphocytic leukemia therapeutics market is expected to create more opportunities in oncology due to promising pipeline and positive clinical data of drug candidates. The existing drugs for the treatment of chronic lymphocytic leukemia is the be most effective treatment. The American Cancer Society, and other regulatory bodies are supporting the chronic lymphocytic leukemia therapeutics market by providing funding and grants. ... Continue Reading

Global Benign Prostatic Hyperplasia Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

The global benign prostatic hyperplasia therapeutics market is expected to witness significant growth, as increased number of effective treatments are available for cancer. Increasing awareness regarding various cancer treatment drugs, technological advancements, and growing demand for safe and effective medications are acting as the major growth drivers for the benign prostatic hyperplasia therapeutics market. Globally, regulatory bodies are adding ... Continue Reading

Global Endometrial Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

Global endometrial cancer therapeutics market is expected to witness significant growth as there are less number of approved drugs for treatment of endometrial cancer, leading to an increased opportunity for the drug manufacturers. High prevalence of cancer and rising demand for safe and effective medications can be attributed as the major drivers of this market. The regulatory bodies such as USFDA and EMA are supporting the growth of the global ... Continue Reading

Global Esophageal Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

Global esophageal cancer therapeutics market is expected to witness significant growth with an increasing awareness regarding cancer treatment and technological advancements. Also, high demand for safe and effective medications and rising prevalence of cancer are driving the growth of the global market. The regulatory bodies such as USFDA, EMA are supporting the growth of the global market by providing funding, designations and grants for speeding up the drug development process. ... Continue Reading

Global Neuroendocrine Carcinoma Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

Global neuroendocrine carcinoma therapeutics market is witnessing significant growth due to large number of marketed drugs and Phase III drugs. Neuroendocrine carcinoma is a tumor that begins in neuroendocrine cells and can spread, or metastasize, to other parts of the body. It starts in the hormone producing cells of the body’s neuroendocrine system. Neuroendocrine tumors can begin in many organs including, lungs, brain and ... Continue Reading

Global Testicular Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

Global testicular cancer therapeutics market is growing with the increasing prevalence of testicular cancer. The market is expected to witness moderate growth, since there are already more than 15 drugs that exist in the market for the treatment of testicular cancer. Increasing prevalence of cancer and rising demand for the medications with better efficacy and less side effects can be attributed as an opportunity for oncology. The regulatory bodies such as ... Continue Reading

Global Oropharyngeal Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

The global oropharyngeal cancer therapeutics market is expected to have significant growth since the pipeline for oropharyngeal cancer is growing rapidly. Also, there are no specific drugs available for the treatment of oropharyngeal cancer providing increased opportunities for the major key players. ... Continue Reading

Global Pancreatic Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

The global pancreatic cancer therapeutics market holds numerous opportunities for the key players, as pancreatic cancer is a highly challenging disease among all types of cancer, which has no specific treatment available for it, as of now. Also, growing incidence of cancer and technological advancements are supporting the growth of the global pancreatic cancer therapeutics market growth. ... Continue Reading

Global Bile Duct Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2023

The global bile duct cancer therapeutics market is expected to witness noticeable growth, in the near future, owing to increasing awareness about cancer and advancements in technologies for cancer treatment. Also, the increasing incidence of cancer is driving the bile duct cancer therapeutics market, globally. ... Continue Reading

Sjögren’s Syndrome Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration and Other Developments

Sjögren’s syndrome is a chronic, autoimmune disease identified by lymphocytic infiltration of exocrine glands and epithelia, which leads to sicca symptoms of dry eyes and dry mouth, and objective evidence of keratoconjunctivitis sicca and xerostomia. Sjogren’s syndrome can be present as primary Sjogren’s syndrome, as itself, or as secondary Sogren’s syndrome, in association with underlying immune conditions. Clinical presentation can vary considerably from relatively mild sicca symptoms, fatig... Continue Reading

Immunoglobulin A (IgA) Nephropathy Therapeutics - Pipeline Analysis, Clinical Trials & Results, Patents, Designations, Collaborations, Patient Size, and Epidemiology Forecast to 2025

IgA nephropathy, also known as Berger’s disease, is a kidney disorder that occurs when IgA antibody gets settled in kidneys. The disease is an auto immune disorder caused due to the accumulation of the IgA which results in inflammation and further damages the glomeruli in kidney.  ... Continue Reading

Rhabdomyosarcoma (RMS) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

RMS is a rare and malignant type of tumor which can arise from skeletal muscles, tendons, or connective tissues. People suffering with RMS may experience different signs and symptoms, some of which may not be seen until the tumor becomes large. The most common symptoms observed in 50% of the children diagnosed with this disease include tumor that can be seen ... Continue Reading

Acute Respiratory Distress Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The acute respiratory distress syndrome therapeutics pipeline is expected to witness nominal growth in the coming year due to the slow research and development activities of the pipeline drugs. Some of the factors driving the growth of the pipeline include approval of new therapies that include but are not limited to, tissue factor antagonists, cluster of differentiation modulators, p38 kinase inhibitors and DNA polymerase inhibitors. Also, increasing awareness ... Continue Reading

Crohn’s Disease Therapeutics - Pipeline Analysis 2018 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The Crohn’s disease therapeutics pipeline is expected to witness extensive growth in the coming year due to emerging biosimilars and novel treatments. In addition, increasing number of pipeline drugs, rising demand for better medications, high prevalence of Crohn’s disease, involvement of the regulatory bodies for funding and designation and increase in the government agencies for the healthcare expenditure act as the major drivers for the Crohn’s disease therapeutics. ... Continue Reading

Cytomegalovirus (CMV) Infection Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The rising number of the research and development activities for the pipeline drugs acts as drivers for the cytomegalovirus infection therapeutics pipeline. The prophylaxis treatment of cytomegalovirus is also increasing due to its effective and safe treatment. The U.S. Food and Drug Administration (USFDA) and European Medicines Agency (EMA) are supporting the cytomegalovirus infection therapeutics pipeline by encouraging the drug development process ... Continue Reading

Fallopian Tube Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The fallopian tube cancer therapeutics pipeline is a major focus for the pharmaceutical companies and researchers since it is one of the most debilitating women’s disease. The invention of novel drug delivery and the targeted therapy is expected to drive the pipeline growth for fallopian tube cancer. Increasing awareness regarding cancer treatment, advancement in technologies, high demand for safe and effective medications and high prevalence of ... Continue Reading

Gallbladder Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Gallbladder cancer therapeutics pipeline is expected to witness increased growth in the future since very less number of drugs are available in the pipeline for the treatment of gallbladder cancer. There is an increase in awareness towards cancer treatments, increasing demand for safe and effective medicines, rising healthcare expenditure and technological advancements are supporting the growth of the gallbladder therapeutics pipeline. ... Continue Reading

Kaposi sarcoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The kaposi sarcoma therapeutics pipeline is expected to grow rapidly as the disease also has the risk of the patient being infected with Acquired Immune Deficiency Syndrome (AIDS). AIDS is the most common risk factors of kaposi sarcoma, which develops in people who are infected with HIV. The Kaposi sarcoma therapeutics pipeline is expected to generate large revenue due to increasing awareness regarding cancer treatments, high demand for safe and ... Continue Reading

Venous Thromboembolism Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The venous thromboembolism therapeutics pipeline is expected to witness considerable growth in the coming year due to the development of novel oral anticoagulants as a reasonable and established treatment option. The regulatory bodies are supporting the drug development process through different types of designations and funding. The pipeline is being driven by different factors such as increasing awareness regarding the venous thromboembolism ... Continue Reading

Hodgkin’s Lymphoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The Hodgkin’s lymphoma therapeutics pipeline is expected to witness considerable growth in the coming years as the researchers are making novel drug delivery system for the treatment for cancer. The government agencies such as National Cancer Institute and American Cancer Society are supporting the growth of the Hodgkin’s lymphoma (HL) therapeutics pipeline by providing funding, designations and grants for speeding up the drug development ... Continue Reading

Multiple Myeloma (MM) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The multiple myeloma therapeutics pipeline is expected to witness considerable growth in the coming year due to high prevalence of the disease. The growth of multiple myeloma therapeutics pipeline is assisted by targeted therapy and new effective treatment. Also, increased awareness among the population about the various cancer treatments has further fueled the growth of the therapeutics pipeline. Increasing healthcare expenditure and ... Continue Reading

Thyroid Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The thyroid cancer therapeutics pipeline is expected to witness considerable growth due to increase in the demand for the targeted drug formulation for the treatment of cancer. Though less number of drugs are available for thyroid cancer treatment, an increasing awareness regarding cancer treatment and high demand for safe and effective medications are driving the therapeutics pipeline. ... Continue Reading

Atopic Dermatitis - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The pipeline for atopic dermatitis therapeutic is expected to witness significant growth in the future due to rising prevalence of the disease and food allergies, which is expected to impact around 20.0% of the global population in the developed countries, according to a research done by Nutrition and Health Department, Nestle Research Centre, in 2015. Many generic drugs are already being given, but with the introduction of biologics, particularly ... Continue Reading

Bipolar Disorder Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Bipolar disorder therapeutic pipeline analysis is expected to increase on account of increasing instances of issues related to depression and other mental disorders, across the world. Major factors driving the pipeline analysis for bipolar disorder are obesity, stress, incidence of nervous system trauma, depression, low market penetration of medicines as very small number of companies are making an analog. In addition, increasing awareness regarding ... Continue Reading

Diabetic Gastroparesis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Diabetic Gastroparesis therapeutic pipeline analysis is expected to grow as observed by the current situation of increasing prevalence of diabetes, globally. Major factors driving the pipeline analysis for diabetic gastroparesis include obesity, incidence of diabetes mellitus, stress conditions and gastroesophageal reflux disease. As there are very limited number of companies are making an analog for treatment and increasing awareness about health issues are ... Continue Reading

Hemophilia Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Hemophilia is a genetic disorder characterized by excessive bleeding and delayed blood clotting. There are two types of hemophilia, hemophilia A (also known as classic hemophilia) and hemophilia B. According to the Centers for Disease Control and Prevention, the incidence of hemophilia stands at, one out of every 5,000 male births and as many as 20,000 males in the U.S., living with either of the two types of hemophilia, presently. The prevalence of hemophilia A is around four times high as compared to the prevalence of h... Continue Reading

Myocardial Infarction Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The myocardial infarction therapeutics pipeline is expected to increase in future due to rise in prevalence of myocardial infarction. Myocardial infarction is also commonly known as heart attack which is symptomatized by decrease in blood supply to the heart muscle due to coronary artery disease. According to American Heart Association, the mortality rate due to cardiovascular disease is higher than other disease. According to British Heart Foundation, in 2015 ... Continue Reading

Neuroblastoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The neuroblastoma therapeutics pipeline is expected to witness considerable growth in the future due to high prevalence of tumour in children. According to the American Cancer Society, around 7.0% of total cancer cases occurred in the age group of 0 to 14, observed as neuroblastoma, with most of the cases being reported at an age of 2 to 3 years. There are various immunotherapies and targeted drug therapies that are being developed for treatment of  ... Continue Reading

Pulmonary Arterial Hypertension Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The pulmonary arterial hypertension therapeutics pipeline is expected to increase in over next few years due to increasing prevalence of pulmonary arterial hypertension. Pulmonary arterial hypertension causes difficulty in blood supply to the lungs due to stiffness, tightening or blockage of a pulmonary artery. Some of the drivers for the growth of pulmonary arterial hypertension therapeutics pipeline include increasing incidence of vascular disease, change in ... Continue Reading

Diabetic Retinopathy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Diabetic retinopathy therapeutic pipeline analysis is projected to grow as perceived by the current situation of increasing prevalence of diabetes, globally. Some of the main factors driving the pipeline analysis for diabetic retinopathy include obesity, incidence of diabetes mellitus, stress conditions and increasing prevalence of diabetic retinopathy, low market penetration since a limited number of companies are making an analog and increasing ... Continue Reading

Growth Hormone Deficiency Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Growth hormone deficiency (GHD) therapeutics pipeline is predicted to increase in future mainly due to the increasing prevalence of the disease, globally. The major factors driving the pipeline of growth hormone deficiency include, increasing prevalence of pituitary dysfunction, low market penetration as very limited number of companies are making an analog of growth hormone. The rising affordability of the drugs and increasing geriatric population also serve ... Continue Reading

Anal Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anal cancer therapeutic pipeline analysis is expected to increase owing to increasing incidence globally, majorly in older adults. Major factors driving towards the pipeline growth for anal cancer include growing rate of sexually transmitted diseases and aging population. Additionally, increasing awareness regarding health issues among people is another major factor fueling the pipeline growth for anal cancer. According to American Cancer Society, the ... Continue Reading

Chronic Myelocytic Leukemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Chronic myelocytic leukemia therapeutic pipeline analysis is expected to grow rapidly due to the increasing prevalence of the disease, globally. Some of the main factors driving the pipeline analysis for chronic myelocytic leukemia include increasing aging population and rising prevalence of chronic myelocytic leukemia, and increasing health awareness. Chronic myelocytic leukemia have high incidence rate in men and is the second most common type ... Continue Reading

Systemic Lupus Erythematosus Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Systemic lupus erythematosus is a chronic inflammatory disease that involves swelling and pain, most commonly on face. The disease affects many parts of the body including skin, joints, kidneys, pleura, pericardium and brain. The systemic lupus erythematosus is caused by impaired immune system due to which the immune system attacks its own tissues and can cause widespread inflammation and tissue damage in the affected organs. As of now there is no cure for systemic lupus erythematosus, but medical interventions and lifest... Continue Reading

Diabetic Foot Ulcer Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Diabetic foot ulcer is a serious complication of diabetes and can be defined as the ulceration in foot along with neuropathy or peripheral artery disease of the lower limb in diabetic patients. Currently, the prevalence of diabetic foot ulcer in diabetic population of the U.S. stands at 4% to 10%. Among diabetic foot ulcer patients, it is estimated that majority (around 60% to 80%) of foot ulcer are capable to heal, while 10% to 15% remain active and around 5% to 24% of them can lead to limb amputation within a period of ... Continue Reading

Chronic Inflammatory Demyelinating Polyneuropathy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Chronic inflammatory demyelinating polyneuropathy pipeline is expected to grow in the next few years on account of increasing prevalence of the disease, which is noticed by progressive muscle weakness, loss of deep tendon reflexes, abnormal sensations, etc. According to a study conducted by American Association of Neuromuscular & Electrodiagnostic Medicine, around 40,000 people in the U.S. get affected from the disease, every year. High prevalence of chronic inflammatory demyelinating polyneuropathy is in turn compell... Continue Reading

Clostridium Difficile-Associated Diarrhea (CDAD)Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The prevalence of clostridium difficile associated diarrhea has been increasing all across the world on account of unchecked use of antibiotics and laxatives by people, which creates a suitable medium for the growth of the bacteria. Clostridium Difficile is a commonly noticed disease in people above 65 years of age, as they tend to consume antibiotics and laxatives for easy and effective bowel movement. The therapeutic pipeline of clostridium difficile associated diarrhea is growing with the involvement of various pharmac... Continue Reading

Fragile-x Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Due to lack of awareness among people regarding genetic disorders which leads to mutations in one’s DNA, the prevalence of fragile-x syndrome is increasing, across the globe. Smoking, alcohol consumption during pregnancy and hereditary disorders are few of the primary reasons to for the increase in prevalence of fragile-x syndrome. The therapeutic pipeline of fragile-x syndrome is expected to grow more rapidly in the future on account of active involvement of pharmaceuticals & biotechnology companies carrying ou... Continue Reading

Cystic Fibrosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Increasing prevalence of cystic fibrosis being witnessed mostly in Europe and the U.S. due to lack of awareness among people towards genetic diseases. In addition, some other factors contributing to the increasing occurrence of cystic fibrosis disease include smoking during pregnancy, hereditary disorder, and premature mortality of infants. The therapeutic pipeline of this particular disease is expected to grow in the future on account of major pharmaceutical companies betting involved in research & development of per... Continue Reading

Small Lymphocytic Lymphoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The rising prevalence of small lymphocytic lymphoma is responsible for the upsurge in research and development of therapeutics that can control progression of the disease, and in turn lead to discovery of new targets that would assist in curing cancer. Increasing adoption of unhealthy lifestyle, unchecked use of pesticides in cultivating crops and fruits along with intake of unhygienic food items causes virus infection such as Hepatitis C and Epstein-Barr virus, which may trigger the incidence of small lymphocytic lymphom... Continue Reading

Myasthenia Gravis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Myasthenia gravis is a chronic autoimmune disorder that acts on neuromuscular junction and leads to the weakening of skeletal muscles. There are various symptoms observed in the patients suffering from myasthenia gravis, such as drooping of one or both eyelids (ptosis), swallowing difficulty, shortness of breath, impaired speech, change in facial expression, and weakness in arms, legs and fingers. Myasthenia gravis is caused due to ineffective transmission of the nerve impulse to the muscles. Various neurotransmitters suc... Continue Reading

Amyotrophic Lateral Sclerosis (ALS) Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Amyotrophic lateral sclerosis is a disease that causes progression in neurodegeneration in brain and spinal cord. In Amyotrophic lateral sclerosis, the muscle does not get adequate nourishment due to which it becomes atrophic. The disease occurs in the lateral region, an area in which spinal cord reflexes are found majorly. Therefore, the degeneration leads to hardening and scarring of muscles in that region. The progressive degeneration of neurons from brain to the spinal cord and spinal cord to the whole body can ultima... Continue Reading

Fabry Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Fabry disease is a type of inherited genetic disease caused due to abnormal deposition of a fatty substance, called globotriaosylcera-mide, in blood vessel walls throughout the body. This further leads to development of other complications, which result in severe morbidities and can also be fatal, in some cases. Anticipated growth of therapeutic pipeline of fabry disease can be attributed to the rareness of the disease, as it is usually found in males at an estimated ratio of one in 40,000 to 60,000 males. Although, the d... Continue Reading

Peripheral Arterial Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

On account of increasing number of cases related to high blood pressure and diabetes, growth in pipeline of peripheral arterial disease is anticipated in the next few years. One of the main causes of peripheral arterial disease is smoking, which leads to the building up of plaque inside the arteries that carry oxygen rich blood. As per the data provided by World Health Organization in 2015, nearly 1.1 billion people were addicted to smoking. Moreover, increasing number of people are being diagnosed with high blood pressur... Continue Reading

Myelofibrosis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Myelofibrosis is a rare disorder characterized by the formation of excessive scar tissue in the bone marrow, that impairs its ability to produce red blood cells. However, it is believed by the researchers that myelofibrosis occurs due to the presence of abnormal red blood stem cells in the bone marrow, that produce mature cells which grow quickly and form scar tissue leading to chronic inflammation. ... Continue Reading

Herpes Simplex Virus (HSV) Infections Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Herpes is an infection caused by a virus known as, herpes simplex virus. It is estimated, that around 3.7 billion people under the age of 50 years are suffering with the herpes simplex virus infection, globally. The disease is categorized into two types: HSV1 and HSV2. HSV1, also known as oral herpes can lead to sores on the mouth and around the lips, HSV2 causes genital herpes. A person can get infected with HSV1 by sharing lip balm, kissing and eating from the same utensils. HSV2 spreads through sexual contact with a pe... Continue Reading

Hereditary Angioedema (HAE) Therapeutics - Pipeline Analysis 2017, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Hereditary angioedema (HAE) is a disease characterized by repeated incidents of swelling (angioedema). The physical signs of the disease include, non-inflammatory swelling of the skin and mucous membrane, that occurs to the subcutaneous tissue in face, arms, buttocks and genitals, and abdominal organs such as stomach, bladder, and urethra. ... Continue Reading

Multiple Sclerosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Multiple sclerosis therapeutic pipeline is expected to grow in future on account of increasing demands of drugs which can completely overcome the rising prevalence of the disease. Currently, multiple sclerosis is mainly impacting regions North America and Europe, some of the other geographies impacted with the disease include Eastern Asia and Sub-Saharan Africa, at very low rate. Major factors driving the growth of pipeline for multiple sclerosis are increasing incidences of multiple sclerosis, stress conditions related t... Continue Reading

Polycystic Kidney Disease (PKD) Therapeutics Pipeline, 2017 - Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Polycystic kidney disease (PKD) affects kidney along with other organs, in which development of cyst interrupts the ability to filter the waste products from blood. Various symptoms are being observed in the patients suffering from the disease; such as pain in the abdomen, back or flank, and it is thought to be caused by enlargement of the cysts in the kidney, bleeding, urinary tract infection, renal colic, or coincidental hypernephroma. ... Continue Reading

Juvenile Idiopathic Arthritis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The expanding pipeline for juvenile idiopathic arthritis can be attributed to the increase in its prevalence. One of the major factor that stimulate the growth of pipeline and research is that the cause of juvenile idiopathic arthritis is not known. The juvenile idiopathic arthritis occurs mostly in children before 16 years of age. Since the disease occurs only in children, so the safety and efficacy concerns of the drugs is given preference so that it can be treated without any side effects. Some of the other factors dri... Continue Reading

Cushing’s Syndrome Therapeutics - Pipeline Analysis 2017, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Cushing’s syndrome is a disease characterized by excess production of cortisol hormone in the blood. It is a severe disease that can be long term and may be life threatening because of the various complications associated with the it such as, diabetes, high blood pressure and mental problems. The common symptoms of the disease include weight gain, roundish face, easy bruising, excessive growth of coarse hair on the face, weakening of the muscles and bones, growth of fat above the collar bone and the back of the neck... Continue Reading

Psoriatic Arthritis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The number of drug candidates in pipeline for psoriatic arthritis are expected to increase on account of increase in the prevalence of psoriasis, globally. Psoriasis is the skin disease which is more common in Caucasian as compared to the African American and Asian Americans. The disease is symptomatized by white and scaly red patches. The prevalence of psoriatic arthritis has been increasing mainly in the patients, who are more susceptible to infection that may activate their immune system. Increase in mortality rate, ot... Continue Reading

Chronic Kidney Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The therapeutics pipeline of chronic kidney disease has been increasing on account of rising prevalence of diabetes and high blood pressure in patients. The diabetes and blood pressure are the main causes of chronic kidney disease, which is also related to cardiovascular disease. Due to altered lifestyle, the chances of incidence of high blood pressure and diabetes is on a rise. Currently, the prevalence of chronic kidney disease is around 14% in Australia, as studied by Oxford Academic Journal of Nephrology Dialysis Tran... Continue Reading

Candidiasis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Candidiasis is a very common type of fungal infection caused by fungus known as candida. Candida is usually found in various parts of our body including mouth, skin or belly and cause no harm. It is only when this fungus gets right environment it multiplies and grows uncontrollably. This condition results in occurring of the infection, known as candidiasis. There are various different types of candidiasis like thrush (oropharyngeal candidiasis), genital yeast infection (genital candidiasis), diaper rash from yeast infecti... Continue Reading

Bronchitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Bronchitis therapeutic pipeline is likely to experience a positive trend in future due to decreasing quality of the air and increasing smoking. Prevalence of bronchitis is increasing due to environmental factors, genetic factors, infections, industrial pollution, less physical activity and smoking. Some of the main factors driving the pipeline analysis for bronchitis include increasing treatment cost, increasing high rate of hospitalizations due to chronic bronchitis, increasing alpha-1-antitrypsin (AAt) deficiency, low m... Continue Reading

Nasopharyngeal Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Nasopharyngeal cancer therapeutic pipeline analysis is likely to grow mainly due to the rising prevalence of nasopharyngeal cancer, globally. Some of the main factors driving the pipeline analysis for nasopharyngeal cancer includes increasing geriatric population, rising tobacco and alcohol consumption and increasing prevalence of nasopharyngeal cancer, untapped market as being a rare form of head and neck cancer and increasing health awareness. According to American Cancer Society, the nasopharyngeal cancer is more commo... Continue Reading

Graves Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Graves disease therapeutic pipeline analysis is expected to increase owing to the high prevalence of the disease. Growing number of cases for hyperthyroidism is a major factor driving the pipeline analysis for Graves disease . In addition, increasing awareness regarding health issues among people is another major factor contributing towards the pipeline for Graves disease. According to American Thyroid Association, the prevalence of Graves disease has increased with increasing hyperthyroidism patients. ... Continue Reading

Chronic Heart Failure Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Chronic heart failure therapeutic pipeline will increase in near future due to increasing cases of the disease. The prevalence of chronic heart failure is increasing globally due to the factors including obesity, diabetes, high blood pressure, cholesterol, less physical activity and tobacco consumption. These factors are contributing in driving the pipeline analysis for chronic heart failure. According to Centers for Disease Control and Prevention, around 5.7 million adults in the U.S. have heart failure and about half of... Continue Reading

Gastrointestinal Stromal Tumor (GIST) - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The gastrointestinal stromal tumor (GIST) pipeline will rise with various collaborations and R&D investments. Hereditary risk and genetic factors play an important role in the development of gastrointestinal stromal tumor. Increasing family history of the disease and genetic factors associated with gastrointestinal stromal tumor and low penetration in the market are contributing towards the development of the pipeline. Additionally, increasing awareness regarding various health issues among people is another major fac... Continue Reading

Global Biosimilars Market Size, Share, Development, Growth and Demand Forecast to 2023

Biosimilars are complex biological products made from living organism that include microorganisms such as bacteria and yeast, humans, and animals. These biological products are similar biological product also known as biological reference product, that have been approved by the U.S. Food Drug and Administration (USFDA). Biosimilars are compared with the biological reference products and licensed by the USFDA. Patent expiration of biological reference product is the key factor leading to development of biosimilars. These a... Continue Reading

Insomnia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Insomnia therapeutic pipeline analysis is expected to experience vast growth in future, with the increasing level of stress being the major contributor for the rising prevalence of the disease. Some of the other major factors driving the pipeline for insomnia include lifestyle diseases, smoking, alcohol and tobacco consumption and increasing health awareness. According to the data by American Academy of Sleep Medicine, every year eight million people suffer from insomnia in the U.S. It is believed that the disease is more... Continue Reading

Glioma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The pipeline for glioma therapeutics is expected to experience rising research activities in future due to raise in funding by the orphan disease organization such as, National Organization of Rare Disorders. Many novel therapies such as, gene therapies, cell therapies are being developed for the treatment of glioma. Various technological advancements in research and development techniques is also be one of the key factors leading to the upsurge in the growth of glioma pipeline therapeutics. Additionally, increasing aware... Continue Reading

Acute Coronary Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The acute coronary syndrome pipeline therapeutics pipeline is expected to increase on account of increasing population, which are at risk of severe cardiovascular disease. High blood pressure, uncontrollable blood sugar level, hypercholesterolemia, smoking are the main causes of developing acute coronary syndrome. Sometimes, stroke, emotional trauma also make a platform for emerging abnormalities in cardiovascular system. Amendments in lifestyle, routine and habit makes a big difference for increasing continuum of cardiov... Continue Reading

Diabetic Macular Edema Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

As estimated worldwide in 2011, the number of peoples with diabetes were around 346 million and its number is unceasingly getting bigger. It is expected to be double in number by 2030. Diabetic retinopathy and diabetic macular edema is occurring, which leads to the vision loss. These adverse conditions mostly occur in patient having high blood sugar level and high blood pressure. Therefore, the consequential increase in growth of diabetic macular edema therapeutics pipeline is observed. ... Continue Reading

Congestive Heart Failure Therapeutics - Pipeline Analysis 2018, Clinical Trials and Results, Patent, Designation, Collaboration, and Other Developments

Prevalence of congestive heart failure is witnessed to have increased, especially in Asia-Pacific and American region, due to rapid change in lifestyle of people, which in turn is results in various lifestyle diseases such as diabetes and high blood pressure. Additionally, other factors such as, sedentary nature of job, high cholesterol diet intake, lack of exercise, pollution, are also contributing to the increasing incidence of congestive heart failure, across the globe. The therapeutic pipeline for congestive heart fai... Continue Reading

Cluster Headache Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Rapidly increasing pace of life, change in lifestyle, higher stress levels, etc., are few of the major factors to which the increasing prevalence of cluster headache scan be attributed. Further, unhealthy dietary intake, smoking, alcoholconsumption and growing levels of pollutionare few other factors which are expected to fuel the incidence of cluster headache problem. The Therapeutic pipeline of cluster headache is expected to grow in future with the participation of various pharmaceutical companies that are focusing on ... Continue Reading

Asthma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The pipeline for asthma therapeutics is expected to experience a positive trend in the future, the increase is mainly attributable to decreasing air quality. The prevalence of asthma is increasing globally due to the factors including environmental factors, genetic factors, air pollution, less physical activity and smoking. These factors contribute immensely in driving the pipeline analysis for asthma. According to World Health Organization, around 235 million people suffered from asthma, in 2013. Asthma related deaths oc... Continue Reading

Prostatitis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

The term prostatitis is defined as microscopic inflammation of the tissue of the prostate gland and it occurs due to a broad range of clinical conditions. The symptoms of prostatitis include difficulty urinating, pelvic area or genitals, pain in the groin, and, sometimes, flu-like symptoms. In 2008, through various studies in the U.S., it was estimated that the prevalence of prostatitis ranges between 2.2% to 9.7%. Due to increased risk of sexually transmitted disease, people become more susceptible to prostatitis. ... Continue Reading

Ewing Sarcoma Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration and Other Developments

Ewing sarcoma is a condition in which formation of cancer or tumor takes place in the bones and soft tissues. It is the second most common type of primary sarcoma found in young adults and children. Ewing sarcoma occurs in ribs, long bones, spine (vertebral column) and pelvis. The prevalence of Ewing sarcoma has increased in the past few years, but the exact cause of the disease is still unknown; some of the risk factors that increase the probability of occurrence of Ewing sarcoma include genetic changes (translocation be... Continue Reading

Uveitis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Uveitis is a chronic inflammatory disease which causes swelling and pain in eye tissues, mainly uvea. It also affects the retina, lens, vitreous and optic nerve, thus hampering the vision of a person. The chances of vision being affected depends on the severity of the disease. People in the age group of 20 to 60 years are most affected by this disease. The severity of the disease can vary from acute to chronic. The different types of uveitis based on the location of the affected tissue includes anterior uveitis, intermedi... Continue Reading

Synovial Sarcoma Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Synovial sarcoma is rare type of cancer and approximately one to three people in every million people are diagnosed with synovial sarcoma every year, globally. The disease occurs frequently in young adults; however, the disease can affect people at any age. Synovial sarcoma is more common in males, and the ratio of the disease stands at 12 males for every ten females. Synovial sarcoma often begins in the legs or arms; however, it can affect any area of the body. The disease is categorized in different subtypes based on mi... Continue Reading

Age-Related Macular Degeneration Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Age-related macular degeneration is a disorder that causes loss of vision in a person due to macula damage; macula is that part of an eye, which helps a person to see, it is made up of millions of light-sensing cells which provide sharp and central vision. Age-related macular degeneration progresses slowly in an individual and can eventually lead to blindness. The most common symptom of Age-related macular degeneration is blurry vision. ... Continue Reading

Dry Eye Syndrome Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Dry eye syndrome, also known as dry eye disease, keratitis sicca and keratoconjunctivitis sicca, is a form of ocular surface and tears disease that results in problems in vision, discomfort and tear film instability, causing potential damage to the ocular surface. It can also overlap with other causes of ocular surface disease such as meibomian gland dysfunction and ocular allergy. The ocular surface consists of seven components including the lacrimal and accessory lacrimal apparatus, the tear film, the nasolacrimal drain... Continue Reading

Oral Mucositis Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Oral mucositis is the most common complication of chemotherapy, and occurs usually in the people suffering from head and neck cancer. It causes damage to mucosal lining of the mouth which results in formation of ulcers and infections. The disease occurs usually occurs after 5 to 10 days of a chemotherapy process in cancer patients. Oral mucositis leads to different problems such as severe pain in mouth, lack of nutrition due to inability to eat, increased risk of infections due to open sores in the oral cavity. The diseas... Continue Reading

Paroxysmal Nocturnal Hemoglobinuria Therapeutic - Pipeline Analysis 2018, Clinical Research and Developments

Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare life-threatening disease characterized by destruction of red blood cells, blood clots, and compromised bone marrow function. Some of the symptoms of the disease include abdominal and back pain, dark urine, easy bruising or bleeding, fatigue or weakness, headache and shortness of breath. The risk factors for PNH include age, obesity and hormone therapy. According to the Johns Hopkins Medicine, approximately, one to one and a half persons per million of the population are ... Continue Reading

Hypercholesterolemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Hypercholesterolemia is a disorder characterised by abnormally increased levels of cholesterol in the blood. The high levels of cholesterol increase a person's risk of developing cardiovascular diseases such as coronary artery disease, which involve build-up of plaque in the coronary arteries, in turn putting a person across the risk of suffering a heart attack. The main causes of hypercholesterolemia include heredity, diet high in saturated fats and cholesterol, other diseases such as diabetes mellitus, renal disease... Continue Reading

Niemann–Pick Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Niemann-Pick Disease is a type of lipid storage disorder characterised by accumulation of fatty substances in organs such as spleen, liver, and brain, eventually causing cell death resulting in malfunctioning of major organ systems. Its pathogenesis involves deficiency of a lysosomal enzyme called acid sphingomyelinase, and is mainly caused by genetic mutation. Niemann-Pick disease is majorly prevalent in North America, South America, Europe, Africa, Asia, and Australia. There are three main types of Niemann-Pick Disease ... Continue Reading

Diabetic Nephropathy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Diabetic nephropathy is a complication of diabetes characterised by damage to the kidneys filtering system. It hampers the ability of kidneys to remove waste products and extra fluid from body. Some of the most common symptoms of diabetic nephropathy include high blood pressure, fatigue, anorexia, headache, skin dryness, and swelling of limbs. The most common risk factors of diabetic nephropathy include diabetes, high blood sugar, high blood pressure, smoking, and heredity. Approximately 40% of people with diabetes eventu... Continue Reading

Allergic Conjunctivitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Allergic conjunctivitis is a disease characterised by inflammation of eyes due to an allergic reaction to substances such as pollen particles or mold spores. It is a collective term for eye infections such as seasonal allergic conjunctivitis (SAC), vernal keratoconjunctivitis (VKC), perennial allergic conjunctivitis (PAC), and atopic keratocongiuntivitis (AKC). Some of the most common forms of eye allergies are the SAC and PAC. According to a study published in the journal, Recent patents on inflammation and allergy drug ... Continue Reading

Post Menopausal Osteoporosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Postmenopausal osteoporosis is a condition affecting millions of women worldwide. It is characterised by decreased bone density in women of postmenopausal age which in turn increases the fragility of bones and making them susceptible to increased risk of sudden and unexpected bone fractures. The cause of postmenopausal osteoporosis is not clearly identified, however, the decrease in bone density is directly linked to deficiency of estrogen, a natural consequence of menopause in women. Since, menopause is an inevitable par... Continue Reading

Atrial Fibrillation Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Atrial fibrillation therapeutic pipeline is expected to increase on account of increasing prevalence of lifestyle disease such as obesity, diabetes, high blood pressure and cholesterol, which in turn lead to increase in the incidence of the disease. Some other prominent factors driving the pipeline analysis for atrial fibrillation include aging population, growing tobacco and alcohol consumption and rising health awareness among people. According to the recently published data by Centers for Disease Control and Prevention... Continue Reading

Acute Kidney Injury (AKI) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Acute kidney injury (AKI) or acute kidney failure is a condition characterized by minor or complete loss of kidney function due to a sudden injury to kidneys. The most common factors associated with higher risk of AKI include hospitalization, especially in intensive care units, old age, peripheral artery disease, diabetes, kidney diseases, high blood pressure, liver diseases, and heart failure. Some of the symptoms that a patient may experience, as the disease prog ... Continue Reading

Psoriasis Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Psoriasis is a medical condition that includes chronic inflammation and scaling on the skin and develops when the skin cells rapidly grow below the surface of the skin and get deposited on the surface before they get mature. Usually this process takes about a month, but in psoriasis it may occur in a few days. Psoriasis leads to the development of thick patches of inflamed skin with a silvery scale covering. These patches are also referred to as plaques and they itch or feel sore. They mostly occur on knees, elbows, other... Continue Reading

Allergic Rhinitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Allergic rhinitis therapeutics pipeline is likely to grow over next few years, on account of increasing air pollution and unchecked exposure of humans to chemicals and radiations, which lead to increase in the incidence of allergic rhinitis. Poor air quality, low market penetration of effective drugs, as most of the available drugs provide temporary relief, and increasing health awareness among people are few other factors expected to propel growth in the allergic rhinitis therapeutics pipeline. According to the latest da... Continue Reading

Progressive Supranuclear Palsy (PSP) Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

PSP occurs when excess Tau protein damages the brain cells and is a supranuclear disease, since it damages the nuclei that control eye movements. The common symptoms of the disease are loss of balance, fast walking, bumping into objects or people, falling, dementia, slurring of speech, difficulty in swallowing, poor working of eyelids, sleep disruption, urinary incontinence, and constipation. Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) scan are used as testing procedures for PSP diagnosis. AbbV... Continue Reading

Immune Thrombocytopenic Purpura Therapeutics (ITP) - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura, is a blood disorder characterised by weakened functioning of clotting of blood. People with the disease have a tendency to bleed or bruise as a result of a low number platelets or thrombocytes which results from the self-destruction of platelets by body’s own immune system. Some of the risk factors for the disease include viral infection, use of certain drugs during pregnancy or other immune disorder. ITP is more common in wome... Continue Reading

Malignant Mesothelioma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Malignant mesothelioma is a rare type of cancer that is characterised by tumor formation in the mesothelium, a tissue layer that covers the pleural organs such as heart, abdomen, lungs and other organs. The biggest risk factor of the disease is exposure to asbestos, a silicate mineral. Some of the major symptoms of the disease include cough, shortness of breath and pain in the chest. The symptoms in malignant mesothelioma could take as long as 30 to 50 years to show. Surgery, chemotherapy and radiotherapy are some of the ... Continue Reading

Critical Limb Ischemia (CLI) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Critical limb ischemia (CLI) is a severe peripheral arterial disease (PAD) characterised by blockage in the arteries of the lower limbs, which in turn reduces blood-flow. The primary cause of the disease is atherosclerosis or the buildup of fatty deposits called plaque in the arteries. Other risk factors for the disease include hypercholesterolemia, obesity, smoking, hypertension and diabetes. Diabetes is a significant risk factor because it is often linked with severe PADs. The most common symptoms of CLI are the ischemi... Continue Reading

Myelodysplastic Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Myelodysplastic syndrome therapeutics pipeline is expected to grow primarily due to the increasing prevalence of the disease as a result of increasing exposure of general population to chemicals and radiation. Some of the main factors driving the pipeline for myelodysplastic syndrome include rising older population, increasing exposure of heavy metals, smoking, tobacco consumption, low market penetration since a limited number of companies are making an analog of marketed drugs and increasing health awareness among people... Continue Reading

Glaucoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Glaucoma is a collection of diseases that injure the optic nerve of the eyes and can eventually lead to loss of vision or complete blindness. People over the age of 60 years, especially Mexican Americans and African Americans and people with a family history of glaucoma are at greater risk of developing glaucoma at some point of time in their lives. It has also been observed that people with blood pressure and heart related problems are more likely to be affected by the condition. As per the estimates of the American Acad... Continue Reading

Alopecia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Alopecia is a skin disease characterised by loss of hair on the scalp, face and less frequently on other parts of the body. According to the National Alopecia Areata Foundation, approximately 6.8 million people in the U.S. and about 147 million people globally are affected by the disease and approximately 2.1% people have a lifetime risk of developing the disease. There are many types of alopecia of which male-pattern baldness is the most commonly encountered type that affects around 50% of males by 50 years of age global... Continue Reading

Huntington’s Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

According to the National Institute of Neurological Disorder and Stroke, Huntington’s disease arises from genetically programmed degeneration of neurons in brain which may lead to emotional disturbance, uncontrolled movements or loss of intellectual faculties. This abnormality causes the loss of memory and perception. The increasing growth in the pipeline for Huntington’s disease is primarily attributed to the limited number of treatments available, as well as the technical advancements in medical field which ... Continue Reading

Mucopolysaccharidosis (Morquio Syndrome) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Mucopolysaccharidosis (Morquio Syndrome), is a group of inherited disorder in which body becomes unable to breakdown the mucopolysaccharides. Accumulation of mucopolysaccharides in cells as well as connective tissues causes the malfunctioning of metabolic enzymes. This malfunctioning may lead to occurrence of variety of health problems. Mucopolysaccharidosis is autosomal dominant in most cases involving X-linked pattern of inheritance. The signs and symptoms of the disease varies by the type of mucopolysaccharidosis. Some... Continue Reading

Lennox-Gastaut Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Lennox-Gastaut Syndrome is a rare form of epilepsy that occurs in childhood and is characterized by seizures and intellectual disability. Adverse conditions such as injury to brain and its malformation, lack of oxygen to the new-born infants, infections of central nervous system and inherited metabolic or degenerative disorders are responsible for occurrence of Lennox-Gastaut Syndrome. Anti-epileptic medications are the main treatment option for Lennox-Gastaut Syndrome. The medication is often complicated in case of paedi... Continue Reading

Narcolepsy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Narcolepsy is a disease that causes prolongation of extreme daytime sleepiness which can leads to muscle weakness and trouble sleeping at night. The complication associated with the disease are cataplexy, hallucinations and sleep paralysis. Due to these complication, the person is at increased risk of developing mental disorders such as schizophrenia. The environmental factors such as toxins that contains heavy metals, pesticides and weed killers and environmental tobacco smoke are thought to be the cause that narcolepsy ... Continue Reading

Nephrotic Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

The growth in the pipeline of nephrotic syndrome is attributed to the increase in prevalence of individuals affected with diabetes, hypertension and hyperlipidaemia. Unhealthy lifestyle and unhygienic crops and fruits are also the factors that are contributing to the growth of therapeutic pipeline of nephrotic syndrome. Environmental factors are also thought to be responsible for occurrence of nephrotic syndrome. Funds from various organizations are contributing to the research and developments in the therapy area which i... Continue Reading

Hepatic Encephalopathy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Due to various risk factors the prevalence of hepatic encephalopathy has been increasing globally. The risk factors for the disease include the consumption of alcohol, drugs addiction for sedatives such as benzodiazepines; often used in treatment of anxiety disorders that can suppress the alcohol withdrawal, challenges in the correct diagnosis and other infections, such as jaundice and deficiency of liver enzymes. According to the Journal of Gastrointestinal & Digestive System, studies proves that in developed countri... Continue Reading

Inflammatory Bowel Disorder Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Globally, the prevalence of inflammatory bowel disorder has been increasing, mainly due to several risk factors such as high pollution due to rapid establishment of industries, smoking and habitual use of non-steroidal anti-inflammatory medicines. The inflammatory bowel disorder therapeutic pipeline is expected to grow in the future mainly due to the emergence of several novel drugs in the market, since various pharmaceutical and biotechnology companies have been focusing to develop drugs for the treatment of this disease... Continue Reading

Fibromyalgia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Fibromyalgia therapeutic pipeline is expected to experience a positive trend in the coming years. Prevalence of fibromyalgia is increasing due to very large number of patients suffering from lifestyle disease, psychological stress, trauma, tension, headaches, anxiety and depression. Some of the significant factors driving the pipeline for fibromyalgia include rising prevalence of fibromyalgia and the increasing health awareness among the population, globally. According to the National Fibromyalgia and Chronic Pain Associa... Continue Reading

Ankylosing Spondylitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Ankylosing spondylitis is an idiopathic disease, associated with HLA-B27, IL23R and ERAP1 genes. Usually, fewer people get affected with ankylosing spondylitis irrespective of activation of genes. Blood test, X-ray test, Magnetic Resonance Imaging (MRI) and physical investigations are some of the ways to effectively diagnose the disease. The disease begins with the inflammation in joints in the vertebrae and pelvic bones and spine. The environmental factors are believed to be the most important risk factor for increasing ... Continue Reading

Cataract Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Cataract is the clouding of eye lens and it can occur in either one or both the eyes. Cataract is generally more common among people over 80 years of age. According to the National Eye Institute, more than half of the Americans suffer from cataract. Eye lens is transparent and light sensitive and is located at the back of the eye. It helps to focus light rays on retina which aids in the formation of clear image. Images at retina are converted into optic signals that are then communicated to the brain. Eye lens is made up ... Continue Reading

Post-Traumatic Stress Disorder (PTSD) Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Post-traumatic stress disorder (PTSD) is a neurological disorder that develops in people who have experienced a scary or a dangerous event. PTSD can occur in a person at any age. According to the National Center of PTSD, around seven to eight out of 100 individuals experience PTSD at some point in their lives in the U.S. PTSD generally occurs more often in women than men. It is natural for a person to be feared during or after a traumatic situation, this fear triggers alteration of many split-seconds in the body to defend... Continue Reading

Spinal Muscular Atrophy (SMA) Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Spinal muscular atrophy is a rare inherited genetic disease that is characterized by loss of nerve cells, known as motor neurons. Motor neurons receive the nerve impulses, which are transmitted from the brain to the spinal cord and, further transmits these impulses to the muscles with the help of peripheral nerves. The loss of motor neurons can lead to atrophy and weakness in the muscles, that are closest to the trunk of the body such as back, hips and shoulders. Spinal muscular atrophy is mainly caused due to the mutatio... Continue Reading

Post-Operative Pain Therapeutics Pipeline Analysis 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pain is an intricate sensation that differs in every individual, even if the cause or the injury is similar. The intensity of pain can be a dull aching or an instant sensation. It may feel like an inexplicable, irritating tickle on the skin. Pain, if left untreated for a long period, negatively impact a person’s mood and well-being. It occurs when the electrical signal travels to the spinal cord due to activation of receptors, which is then transmitted to the brain. The spinal cord acts as a transmission center, whe... Continue Reading

Global Immunotherapy Drugs Market Size, Share, Development, Growth and Demand Forecast to 2023

Immunotherapy drugs refer to the drugs that enhance, suppress or stimulate the body’s immune system and modulate the immune responses of the body. Immunotherapy drugs improve the immune system of the body, restrict the growth of the diseases, and enhance the immunity to fight against the diseases.  These drugs are used in cancer treatment to restrict the growth of cancer cell and prevent it from growing to the other parts of the body. Immunotherapy drugs are an effective treatment for autoimmune diseases, immun... Continue Reading

Charcot-Marie-Tooth Disease (CMT) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Charcot-Marie-Tooth disease (CMT) is a neurological disorder, but it is not a life-threatening disease. Charcot-Marie-Tooth disease does not affect the brain but causes damage to the peripheral nerves; tracts of nerve cell fibres that connect the brain and spinal cord to muscles and sensory organs. Charcot-Marie-Tooth disease is not curable, but the disease generally progresses slowly, and it does not affect expected life span. The therapy includes physical therapy, occupational therapy and orthopedic devices. ... Continue Reading

Duchenne Muscular Dystrophy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Duchenne muscular dystrophy is an inherited disorder that involves muscle weakness that worsen quickly and is a fatal genetic disorder diagnosed in the childhood. The fatal disease is caused by the mutation in the Duchenne gene found on the X-chromosome that encodes for dystrophin. The disease progression leads to muscle weakness and serious medical problems including issues related to the heart and lungs. It has been observed that young men with Duchenne muscular dystrophy live only till late twenties. ... Continue Reading

Bone Marrow Transplant Rejection Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Bone marrow transplant rejection is a complication that occurs after a stem cell or bone marrow transplant has been done, as the newly transplanted donor cells attack the transplant recipient's body. The symptoms of the bone marrow transplant rejection include chest pain, chills, drop in blood pressure, fever, flushing, headache, hives, nausea, pain and shortness of breath. The disease is mainly treated through immunosuppressive drugs. ... Continue Reading

Bladder Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Bladder is a hollow organ in the lower part of the abdomen, that stores urine before passing it out of the body. The most common type of bladder cancer is transitional cell carcinoma that begins in the urothelial cells lining the bladder. The other two types of bladder cancer include squamous cell carcinoma and adenocarcinoma. Some of the symptoms associated with bladder cancer include blood in the urine, frequent urination, pain during urination, urinary incontinence, and pain in the lower part of the tummy or back. ... Continue Reading

Botulism Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Botulism is a rare illness caused by a toxin that attack a body’s nerves. Botulism toxin is made by Clostridium botulinum and sometimes Clostridium butyricum and Clostridium baratii bacteria. The symptoms of botulism usually start with weakness of the muscles that control the eyes, face, mouth, and throat. This weakness can further spread to the neck, arms, torso, and legs. Botulism can also weaken the muscles involved in breathing, which can lead to difficulty breathing and can be fatal. ... Continue Reading

Becker Muscular Dystrophy (BMD) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Becker muscular dystrophy is an inherited muscle wasting diseases caused by a gene abnormality (mutation) that results in deficient or abnormal production of the dystrophin protein (dystrophinopathies). Becker muscular dystrophy follows x-linked recessive inheritance and is mostly found in males, but some females are also affected. Becker muscular dystrophy usually begins in the teens or early twenties and symptoms vary in affected individuals. Muscle deterioration progresses slowly but usually results in the need for a w... Continue Reading

Bacterial Vaginosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Bacterial vaginosis is a common vaginal infection, and is classified as a sexually transmitted infection (STI). Bacterial vaginosis occurs when there is a change in the natural balance of bacteria in vagina. Bacterial vaginosis is usually treated with antibiotic tablets or gel. The disease usually occurs in the women in the age group of 15-44. Although, the exact cause of bacterial vaginosis is unknown, it is believed that the infection typically occurs in sexually active women. The disease is linked to an imbalance of &l... Continue Reading

Benign Prostatic Hyperplasia (BPH) Procedures by Type (Green Light Lasers, Holmium Lasers, Thulium Lasers, TURP, TUIP, TUMT, TUNA, Rezum, HIFU & Water Induced Therapies, UroLift), by End User (Hospitals, Specialty Clinics, Ambulatory Surgery Centers), by Geography (Germany, U.K., France, Italy, Spain, U.S., Canada, Australia, Japan, South Korea) - Global Procedures, Developments, Growth and Forecast, 2013-2023

Benign Prostatic Hyperplasia (BPH) refers to an enlarged prostate gland. The prostate gland surrounds the urethra, the tube that carries urine from the bladder out of the body. As the prostate gets bigger, it may squeeze or partly block the urethra, causing problems while urinating. BPH is common in aging men, and about half of all men between the ages of 51 and 60 suffer from BPH. It has been observed that up to 90% of men above the age of 80 years have BPH. The treatment methods for BPH include medications, transurethra... Continue Reading

Bronchiectasis Therapeutics - Pipeline Analysis 2017, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Insmed Incorporated is in the process of developing Amikacin Liposome Inhalation Suspension (ALIS) and INS1007 for the treatment of bronchiectasis. Many companies are more focused on developing their drug candidates as small molecule with the inhalation route of administration in the bronchiectasis therapeutics pipeline. ... Continue Reading

US Benign Prostatic Hyperplasia (BPH) Procedures by Type (Green Light Lasers, Holmium Lasers, Thulium Lasers, TURP, TUIP, TUMT, TUNA, Rezūm, HIFU & Water Induced Therapies, UroLift) – Procedures, Development, Growth and Forecast, 2013-2023

Growing aging population, rising prevalence of BPH disorders, technological advancements in BPH procedures and rising awareness about BPH disorders and the treatments available are some of the factors increasing the number of BPH treatment procedures in the U.S. However, the adoption of BPH procedures in the U.S has been facing certain challenges such as side-effects associated with BPH treatment procedures and unfavourable healthcare reforms in the U.S., which is likely to impede its growth during the forecast period. Mo... Continue Reading

Constipation Therapeutics – Pipeline Analysis 2017, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Constipation is a common functional GI disorder that is most prevalent in the elderly and female population and is characterized by lumpy or hard stools, straining, low back pain, pain on defecation, rectal bleeding, abdominal bloating, and feeling of incomplete defecation. The disease can have significant adverse effects on the health and quality of life, which may further lead to psychological and social distress. ... Continue Reading

Hypothyroidism Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Hypothyroidism, also known as underactive thyroid disease, is a disease caused by the inflammation of the thyroid gland. Some of the other causes of hypothyroidism may also include radiation therapy, thyroid surgery and pregnancy. The symptoms of hypothyroidism include constipation, low muscle tone, stomach bloating, swollen tongue and extreme sleepiness. According to the data published by the American Thyroid Association, more than 12% of the U.S. population will develop a thyroid condition during their lifetime. ... Continue Reading

Hypogonadism Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Hypogonadism, also known as gonad deficiency, is a disease that involves less or no production of sex hormones. The different types of the hypogonadism include primary hypogonadism and central hypogonadism or secondary hypogonadism. The disease is caused by several factors including autoimmune disorders, genetic disorders, severe infections, liver and kidney diseases, undescended testes, radiation exposure, hemochromatosis, pituitary disorders, inflammatory diseases, obesity, nutritional deficiencies and surgery. ... Continue Reading

Hypertension Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Hypertension is a medical condition that involves high blood pressure against the walls of blood vessels. The normal systolic pressure is 120 mmHg while normal diastolic pressure is 80 mmHg. Hypertension is usually caused by acute stress and intense physical exercise. The risk factors associated with the hypertension include obesity, chronic kidney disease, cardiovascular disease, low potassium in the diet, alcohol and tobacco use, physical inactivity and a salt-rich diet associated with processed and fatty foods. ... Continue Reading

Hyperlipidemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Hyperlipidemia refers to the condition of elevated amount of lipids and cholesterol in the bloodstream. The two major types of lipid abnormalities are characterized by either high blood levels of triglycerides (known as hypertriglyceridemia) or high blood cholesterol levels (known as hypercholesterolemia). ... Continue Reading

Hepatitis D Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Hepatitis D is a viral infection caused by the hepatitis D virus (HDV), which is a ribonucleic acid (RNA) virus that requires hepatitis B virus (HBV) for its replication. It attacks the liver and can cause both acute and chronic disease. Hepatitis D infection cannot occur in the absence of hepatitis B virus. The risk factors associated with hepatitis D includes hepatitis B infection, frequent blood transfusions and abuse injectable or intravenous (IV) drugs, such as heroin. Eiger BioPharmaceuticals, Inc. is in the process... Continue Reading

Grass Pollen Allergy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Grass pollen allergy is an allergy caused by the pollen that comes from grasses and it tends to start growing in the spring. The symptoms associated with the grass pollen allergy includes cough, runny nose and itchy eyes. Dry winds, unmowed lawn and certain foods such as melons, oranges, peaches, celery and tomatoes can make the allergy worse. ... Continue Reading

Gouty Arthritis (Gout) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Gouty arthritis, also known as gout, is a type of arthritis that attack joints, and with time it also attacks tendons and other tissues. It is caused by increase in the uric acid in the blood. Alcohol abuse, obesity and high consumption of diuretics can increase the risk of developing gout. The most common symptoms of gout include swelling, pain and rudeness. ... Continue Reading

Renal Cell Carcinoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Renal cell cancer, also known as kidney cancer or renal adenocarcinoma, is a disease caused by the presence of malignant or cancerous cells in the lining of tubules in the kidney. Smoking and consumption of certain painkillers for a long duration of time can increase the risk of developing renal cell carcinoma. ... Continue Reading

Neuroendocrine Carcinoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Neuroendocrine carcinoma begins in the neuroendocrine cells and can metastasize to other parts of the body. It develops in the hormone producing cells of the body’s neuroendocrine system. Neuroendocrine carcinoma can develop in many organs, including gastrointestinal tract, lungs and brain. The risk factors associated with neuroendocrine cancer include, family history, immune system suppression, sun exposure and arsenic exposure. ... Continue Reading

Pancreatic Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pancreatic cancer develops when pancreas starts developing abnormally. Pancreatic cancer is categorized into two different types, which includes exocrine pancreatic cancer and endocrine pancreatic cancer. Tobacco use, obesity, chemical exposure, family history, diabetes, chronic pancreatitis, liver cirrhosis and inherited genetic syndromes are the risk factors associated with pancreatic cancer. ... Continue Reading

Hepatocellular Carcinoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Hepatocellular carcinoma is the liver malignancy that develops in the patients suffering from cirrhosis and chronic liver diseases. The disease is caused by liver diseases including hepatitis B or hepatitis C, cirrhosis, alcohol abuse, obesity, diabetes, iron storage disease and aflatoxin. Some of the common symptoms of hepatocellular carcinoma include, pain, lump in upper belly, bloating, weight loss, loss of appetite, nausea, fatigue and fever are the. According to American Cancer Society, around 40,710 new cases of pri... Continue Reading

Wnt Signaling Pathway Inhibitors Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Pharmaceutical companies are using different technologies for better development of drug candidates. These technologies can be helpful in the development of drugs as combination therapies or single agent therapies. They also allow the development of specific targeted therapies with better drug delivery. For instance, Samumed's technology platform can modulate the Wnt signaling pathway in selected tissues with small molecules. ... Continue Reading

Head and Neck Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Head and neck cancer usually develops in the squamous cells that line the moist, mucosal surfaces inside the salivary glands, and head and neck. Alcohol use, tobacco use are major risk factors associated with the head and neck cancer. The other risk factors include human papillomavirus (HPV) infections, oral health, radiation exposure, preserved or salty foods, occupational exposure, ancestry, Epstein-Barr virus infection, and others. According to the American Society of Clinical Oncology (ASCO), head and neck cancer acco... Continue Reading

Gaucher Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Gaucher disease is a type of a lysosomal storage disorder that often causes liver and spleen enlargement, bone issues and blood problems. The disease involves fatty lipid deposition in certain organs and bones. The disease is treated by bone marrow transplantation and enzyme replacement therapy (ERT). Gaucher disease is categorized into type I, II and III. According to the data published by National Organization for Rare Disorders (NORD), Gaucher disease type I is the most common type, accounting for more than 90% of case... Continue Reading

Fanconi’s Anemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Fanconi’s anemia is an inherited genetic disorder that affects the bone marrow and results in the decreased production of all types of blood cells. The symptoms associated with the disease include decreased blood cell number, bone problems, vitiligo, deafness, eye problems, short height, small head, small testicles and genital changes. The disease can be diagnosed by bone marrow biopsy, complete blood count, hearing test, CT scan and MRI. ... Continue Reading

Escherichia Coli (E. coli) Infections Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Escherichia coli (E. coli) infections is a disease caused by coming into contact with the stool or feces, of animals or humans. The symptoms associated with the disease include diarrhoea, stomach cramps, nausea and vomiting. The disease in its chronic phase can be diagnosed by observing the symptoms such as pale skin, fever, weakness and bruising.  ... Continue Reading

Epstein-Barr Viral Infections Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Epstein-Barr virus infections is a disease associated with the glandular fever and usually occurs in the childhood. The symptoms associated with the disease include fever, fatigue, lack of appetite, sore throat, swollen glands and weakness. The virus is found in the saliva, blood and semen and can spread through kissing an infected person, using infected person’s toothbrush, blood transfusion and organ transplant. ... Continue Reading

Encephalopathy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Encephalopathy is a disease that affects the structure and functioning of the brain, which can be permanent or temporary. The different types of encephalopathy include chronic traumatic encephalopathy, glycine encephalopathy, Hashimoto’s encephalopathy, hepatic encephalopathy, hypertensive encephalopathy, hypoxic ischemic encephalopathy, toxic-metabolic encephalopathy, infectious encephalopathies, uremic encephalopathy and Wernicke encephalopathy.  ... Continue Reading

Encephalomyelitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Encephalomyelitis involves inflammation of spinal cord or brain. The various types of the disease include acute disseminated encephalomyelitis, encephalomyelitis disseminate, AntiMOG associated encephalomyelitis, equine encephalomyelitis, myalgic encephalomyelitis, experimental autoimmune encephalomyelitis, progressive encephalomyelitis with rigidity and myoclonus and AIDS related encephalomyelitis. ... Continue Reading

Arrhythmias Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Arrhythmia refers to any change from the normal sequence of electrical impulses, causing abnormal heart rhythms. A fast heart rate (in adults, more than 100 beats per minute) is known as tachycardia. A slow heart rate (less than 60 beats per minute) is known as bradycardia. When the heart does not beat properly, it cannot pump blood effectively. When the heart does not pump blood effectively, the lungs, brain and all other organs cannot work properly and may shut down or be damaged. Some arrhythmias are so brief that the ... Continue Reading

Acinetobacter Infections Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Acinetobacter infections are caused by the bacterium Acinetobacter baumannii. The disease has emerged as a major cause of healthcare-associated infections. The virulence of Acinetobacter species is low, but these are capable of causing infection in organ transplants and febrile neutropenia. Most of the Acinetobacter isolates recovered from hospitalized patients, particularly those recovered from respiratory secretions and urine, represent colonization rather than infection ... Continue Reading

Acute Myeloid Leukemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

According to National Cancer Institute, a part of the U.S. National Institutes of Health, acute myeloid leukemia is a type of cancer that affects the blood and bone marrow. It is characterized by overproduction of immature white blood cells, myeloblasts or leukemic blasts. These cells crowd the bone marrow, preventing it from making normal blood cells. They can also spill out into the blood stream and circulate around the body. Takeda Pharmaceutical Company Limited is in the process of developing, Alisertib, for the treat... Continue Reading

Acute Pain Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Acute pain is defined as a type of pain that is directly related to soft tissue damage such as sprained ankle. The pain generally lasts for less than 3 to 6 months. The acute pain remains for a short duration of time and is gradually resolved, as the injured tissues heal. The chronic pain is relatively more sharp and severe as compared to acute pain. Acute pain is triggered by a specific disease or injury, skeletal muscle spasm and sympathetic nervous system activation, and is self-limited. ... Continue Reading

Adrenoleukodystrophy (Adrenomyeloneuropathy/ Schilder-Addison Complex) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Adrenoleukodystrophy (Adrenomyeloneuropathy/ Schilder-Addison Complex) is a X-linked rare disorder that generally occurs in males. Adrenoleukodystrophy commonly affects the nervous system and the adrenal glands, which are small glands located on top of each kidney. As a X-linked disorder, Adrenoleukodystrophy presents is mostly found in males and occurs in about one out of every 17,000 births. ... Continue Reading

Allergic Asthma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Asthma refers to the narrowing of the airway of lungs caused by inflammation in the air passage resulting from both genetic and environmental influences. Allergic asthma leads to allergies when the immune system overreacts to the presence of a harmless substance known as allergen. Some people may develop breathing problems from inhaling allergens. It occurs when the airways swell as part of an allergic reaction. ... Continue Reading

Alpha-1 Antitrypsin (AAT) Deficiency Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Alpha-1 antitrypsin deficiency is an inherited disorder that may cause lung disease and liver disease. The sign and symptoms of people with alpha-1 antitrypsin deficiency usually develop as lung disease between the age of 20 and 50 years. The earliest symptoms of Alpha-1 antitrypsin deficiency include shortness of breath following mild activity, reduced ability to exercise, and wheezing. Other signs and symptoms can include unintentional weight loss, fatigue, recurring respiratory infections, and rapid heartbeat upon stan... Continue Reading

Amyloidosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Amyloidosis is a rare and serious protein deposition disease and is caused by an abnormal protein known as amyloid that builds up in the tissues or organs. As the amount of amyloid protein deposits increases in a tissue or organ, they interfere with the tissue or organ’s healthy function. Eventually, the amyloid protein deposits can cause symptoms and organ failure and sometimes can be fatal. ... Continue Reading

Anaphylaxis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anaphylaxis is a severe and rapid systemic allergic reaction to a trigger substance, known an allergen. Minute amounts of trigger substances may cause a life-threatening anaphylactic reaction. Anaphylaxis may occur after ingestion, inhalation, skin contact or injection of a trigger substance. The most severe type of anaphylaxis is known as anaphylactic shock that is usually fatal, if untreated. Anaphylaxis requires immediate medical treatment, including an immediate injection of epinephrine and a trip to a hospital emerge... Continue Reading

Anaplastic Large Cell Lymphoma (ALCL) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anaplastic large cell lymphoma (ALCL) is a rare type of non-Hodgkin lymphoma. Anaplastic large cell lymphoma is made up of either malignant T-cells (type of cells in the immune system), or null-lymphocytes (lack both B or T-cell markers). The presence of the protein, ‘CD30 antigen’ on the surface of lymphoma cells is a distinctive feature of the ALCL. ALCL occurs in two forms, systemic ALCL and primary cutaneous ALCL. Systemic ALCL can affect all organs in the body and it is aggressive while primary cutaneous ... Continue Reading

Anaplastic Astrocytoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anaplastic astrocytoma is a rare malignant brain tumor that develops from certain star-shaped brain cells known as astrocytes. Astrocytes and similar cells form tissue that surrounds and protects other nerve cells found within the brain and spinal cord. Collectively, these cells are known as glial cells and the tissue they form is known as glial tissue. Tumors that arise from glial tissue, including astrocytomas, are collectively referred to as gliomas. The symptoms of anaplastic astrocytomas vary depending upon the speci... Continue Reading

Androgenic Alopecia Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Overview Androgenic alopecia is a genetic disorder that affects both men and women and is characterized by hair loss in both Donthe sexes. Androgenic alopecia is also known as male-pattern baldness in men and female-pattern baldness in women. The predisposing factors for androgenic alopecia include allergies, burns, irritants, injuries, infections, and toxins. In men, hair loss occurs in a well-defined pattern, beginning from above the temples and over a period, the hairline recedes to form a characteristic "M&qu... Continue Reading

Anxiety Disorders Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anxiety disorders involves a person experiencing more than temporary worry or fear. For a person with an anxiety disorder, the anxiety does not go away and can get worse over a period of time. The feelings can interfere with daily activities such as job performance, school work, and relationships. Anxiety is a normal reaction to stress and can be beneficial in some situations. It can alert a person about any future dangers, thereby helping them to prepare and pay attention. Anxiety disorders differ from normal feelings of... Continue Reading

Anthrax Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anthrax is an infectious disease caused by rod-shaped, gram-positive bacteria known as Bacillus anthracis. Anthrax can be found naturally in soil and commonly affects domestic and wild animals globally. It has been observed that people can get sick with anthrax if they come in contact with infected animals or contaminated animal products. Contact with anthrax can cause severe illness in both humans and animals. ... Continue Reading

Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides are a heterogeneous group of diseases corresponding to necrotising inflammation of small vessels with a wide range of clinical presentations. ANCA disease process is characterized by necrotizing inflammation of small vessels, the relative paucity of immune deposits and an association with detectable circulating ANCAs. ... Continue Reading

Peptide Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Peptides are the small molecules composed of aminoacids which are connected with each other with peptide bond. Peptides play an important role in various anabolic and catabolic biological processes. They play a key role in cell signaling pathways, hormonal systems, enzymatic systems immune system and various other important functions of the body. ... Continue Reading

Aspergillosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Aspergillosis is an infection caused by Aspergillus, a common mold (a type of fungus) that breeds indoors and outdoors. Most people breathe in Aspergillus spores every day without getting sick. However, people with a weak immune system or lung diseases are at a higher risk of developing health problems due to Aspergillus. Some of the health problems caused due to Aspergillus include allergic reactions, lung infections, and infections in other organs of the body. ... Continue Reading

Brain Edema Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Brain edema, also known as cerebral edema, occurs as a result of an increase in brain fluid content. Brain edema causes swelling of the brain due to excessive fluid collection in the chambers or ventricles of the brain or accumulation of fluid within the brain tissue itself. The causes of cerebral edema include traumatic brain injury, ischemic stroke, haemorrhages, tumors and infections (toxoplasmosis, meningitis, subdural empyema). Cerebral edema may or may not be associated with increased intracranial pressure. It may o... Continue Reading

Brain Ischemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Brain ischemia occurs when the blood supply to any part of the brain is interrupted, resulting in tissue death and loss of brain function. The most common cause of brain ischemia stroke is atherosclerosis. Other conditions that may result from brain ischemia are stroke, cardiorespiratory arrest, and irreversible brain damage. The causes of brain ischemia can vary from sickle cell anemia to congenital heart defects. The symptoms of brain ischemia include loss of movement of body area, weakness, numbness, decreased vision, ... Continue Reading

Breast Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Breast cancer occurs when cells in breast begin to grow uncontrollably. Cancer cells usually form tumor and can be felt as a lump or seen under x-ray. Mostly, breast cancer begins in the duct that carries milk to the nipple, while some breast cancer cells start in the glands that make breast milk. As per National Institutes of Health (NIH), in the U.S., 14.6% of all new cancer cases diagnosed every year are of breast cancer. HER2 (human epidermal growth factor receptor 2) is a gene that plays a role in the developmen... Continue Reading

Bullous Pemphigoid Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Bullous pemphigoid is a chronic autoimmune skin disorder that cause generalized, pruritic, bullous lesions in elderly patients. Bullous pemphigoid occurs more often in patients aged 60 years and above, but can also occur in children. IgG autoantibodies bind to certain hemidesmosomal antigens (BPAg1, BPAg2), resulting in the activation of complement system to form a sub epidermal blister. ... Continue Reading

Burkitt Lymphoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Burkitt lymphoma is a rare, highly aggressive B-cell non-hodgkin lymphoma. Burkitt lymphoma disease may affect jaw, central nervous system, bowel, kidneys, ovaries, or other organs. There are three main types of Burkitt lymphoma: endemic, sporadic, and immunodeficiency-related. Endemic Burkitt lymphoma is the most common of the three types, originating in Africa, where it is still the most common childhood cancer. Endemic Burkitt lymphoma is rare outside of Africa. Sporadic Burkitt lymphoma occurs throughout the world. Th... Continue Reading

Cachexia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Cachexia is a major cause of weight loss and increased mortality that affects more than five million people in the U.S. Clinically, cachexia manifests with excessive weight loss in the setting of ongoing disease, usually with disproportionate muscle wasting. Differentiation from other syndromes of weight loss is pivotal to prompt recognition and effective management of cachexia. ... Continue Reading

Canavan Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Canavan disease is a rare inherited disorder that damages the ability of nerve cells (neurons) in the brain to send and receive messages. Canavan disease is one of a group of genetic disorders, known as leukodystrophies. Leukodystrophies disrupt the growth or maintenance of the myelin sheath, which is the covering that protects nerves and promotes the efficient transmission of nerve impulses. Neonatal/infantile Canavan disease is the most common and most severe form of the condition. Affected infants appear normal for the... Continue Reading

Cancer Pain Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Cancer pain is the most common symptom in the patients which is caused by tumour pressing on other organs, nerves, or bones in the body. Chemotherapies also causes numbness and tingling sensations in patient’s hands or feet while radiotherapy results in skin irritation and redness. Cancer pain can be categorized into two types, including acute pain and chronic pain. The severity of pain depends upon the type of cancer, location of the cancer, stage of the cancer and presence of any nerve damage due to cancer or canc... Continue Reading

Cervical Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Cervical cancer is an abnormal growth of the cervix tissues. The cervix is the lower narrowed end of the uterus, also called birth canal, which leads from uterus to vagina. There are two types of cervical cancer namely squamous cell carcinoma and adenocarcinoma. Almost 80% to 90% of the of cervical cancer are squamous cell carcinoma. Squamous cell carcinoma begins in flat and thin cells that line the cervix while adenocarcinoma begins in the cervical cells that make mucus and other fluids. ... Continue Reading

Colorectal Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Colorectal cancer refers to a cancer type that starts in the colon or the rectum, and begins on the inner lining of colon or rectum known as polyp. The type of polyp known as adenomatous polyps are more likely to turn into cancer and are termed as precancerous conditions. The symptoms include rectal bleeding, change in bowel habit, abdominal discomfort, weakness or fatigue and weight loss. According to National Institutes of Health (NIH), around 8% of all new cases of cancers are of colorectal cancer, in the U.S... Continue Reading

Batten Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Batten disease is a fatal, inherited disorder of the nervous system that typically begins in the childhood. Early symptoms of Batten disease usually appear between the age of five to 10 years, when parents or physicians may notice a previously normal child has begun to develop vision problems or seizures. In some cases, the early signs are subtle, taking the form of personality and behaviour changes, slow learning, clumsiness, or stumbling. It has been observed that over a period of time, affected children suffer from cog... Continue Reading

Atherosclerosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Atherosclerosis refers to situation when fatty substance deposits in the arteries and leads to its clogging. The fatty deposition in the arteries is known as plaque. The plaques are made up of cholesterol, fatty substances, cellular waste products, calcium and fibrin (a clotting material in the blood). Sometimes deposits in arteries are compared to a plumbing problem. ... Continue Reading

Eating Disorders Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Eating disorders are disorders that can cause serious and fatal illness in the body. There are several types of eating disorders such as anorexia nervosa, bulimia nervosa, emotional overeating, binge eating disorder, and others. People with anorexia nervosa consider themselves as overweight even when they are dangerously underweight. People with bulimia nervosa generally have frequent episodes of uncontrollable eating. People with binge eating disorder generally have no control over eating and they are often obese. ... Continue Reading

Aphasia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Aphasia is a type of neurological disorder that is caused by factors which lead to damage to the language areas of the brain such as stroke, brain tumour, brain infection, gunshot wounds, and certain progressive neurological disorders such as Alzheimer’s disease and Parkinson’s disease. Aphasia is categorized into two types, non-fluent aphasia and fluent aphasia. ... Continue Reading

Arterial Stiffness Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Arterial stiffness is a type of cardiovascular disorder that occurs due to arteriosclerosis and aging. Stiffness can be defined as the viscoelastic property that anticipate the relationship between change in volume and change in pressure. Due to decrease in capacity of reservoir and recoiling elasticity, the diastolic pressure decreases and pulse pressure increases. ... Continue Reading

Arteriosclerosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Arteriosclerosis is a type of cardiovascular disorder characterised by build-up of plaque inside arteries. Plaques are generally made up of fat, calcium, cholesterol, and other substances in the blood. The plaque formation leads to decrease in supply of oxygen-rich blood to the organs in the body. The complications associated with arteriosclerosis include stroke and heart attack. Some of the risk factors associated with arteriosclerosis are high blood pressure, insulin resistance, diabetes, obesity, lack of physical activ... Continue Reading

Arteriovenous Fistula Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, And Other Developments

Arteriovenous fistula is a cardiovascular disorder characterized by an abnormal connection between a vein and an artery. In a person having arteriovenous fistula, the blood flow pathway from arteries to the vein is altered and it bypasses the capillaries due to which the tissues below the bypassed capillaries get diminished blood supply. The disease generally occurs in legs. ... Continue Reading

Arthritis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Arthritis is an inflammatory disorder that occurs in joints and surrounding tissues. There are six types of arthritis namely osteoarthritis, autoimmune arthritis, psoriatic arthritis, juvenile arthritis, gout arthritis, and infectious arthritis. Symptoms of arthritis can include pain, swelling, redness, stiffness and decrease in movement. Some of the risk factors associated with arthritis are aging, obesity, joint injury, and family history. Certain laboratory tests such as blood test, and urine test, and imaging techniqu... Continue Reading

Ascites Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Ascites is one of the complications of liver diseases and is characterised by collection of fluid in the abdomen that causes swelling. More than 25 ml of fluid may accumulate in the peritoneal cavity. The disease can be caused by portal hypertension and low level of albumin protein in the blood. Hepatitis C or B infection, abdominal cancer, pancreatitis, congestive heart failure, portal vein thrombosis, and chronic alcohol abuse are the risk factors associated with ascites. Ascites can be symptomatized by bloating, sudden... Continue Reading

Acute Leukemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Acute leukemia is also known as cancer of blood cells in which immature blood cells modify into cancer cells. The disease arises from bone marrow and causes formation of numerous large blood cells. Leukemia is categorized into five different types namely acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, and hairy cell leukemia. Leukemia can produce be symptoms such as fever, recurrent nosebleeds, bone pain, swollen lymph nodes, persistent fatigue, petechiae, ... Continue Reading

Anaplastic Oligoastrocytoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anaplastic oligoastrocytoma is a type of brain tumour in which certain brain cells such as oligodendrocytes and astrocytes, rapidly increase in number and form a mass. The disease is also called mixed glioma because it involves two types of cells. Anaplastic oligoastrocytoma generally occurs in the cerebrum region. Some of the symptoms of anaplastic oligoastrocytoma include seizures, headache and change in personality. The disease can be treated by surgical methods that involve removal of the tumour. ... Continue Reading

Aneurysm Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Aneurysm is a type of disorder that causes bulge formation in arteries. The disease generally occurs due to damaging of arteries. The bulge formation leads an increased force against an injured wall inside the artery. This further leads to rupturing of the artery and severe bleeding. Aneurysm mostly occurs in aorta that supply oxygen-rich blood from the heart to other parts of the body. ... Continue Reading

Aneurysmal Subarachnoid Hemorrhage Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Aneurysmal subarachnoid hemorrhage is a disorder that is characterized by loss of consciousness, sudden severe headache, epileptic seizures, and neurological symptoms such as hemisensory or motor symptoms and dysphagia. The disease can be diagnosed by blood count test, urea and electrolytes test, serum glucose test, chest radiography, lumbar puncture, and computed tomography. The complications associated with aneurysmal subarachnoid haemorrhage include hydrocephalus, seizures, hyponatremia, immediate cerebral ischemia, an... Continue Reading

Angiosarcoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Angiosarcoma is a type of soft-tissue sarcoma that arises from the endothelial cells. The disease is generally aggressive and characterized by extensively infiltrating anaplastic and rapidly proliferating cells. Angiosarcoma can occur in any part of the body but it is mostly found in the skin and soft tissues. Head and neck angiosarcoma accounts for around 50% of the cases of angiosarcoma. Cutaneous angiosarcoma is a type of angiosarcoma which is mostly found in females whereas, in males, bone and soft tissue sarcoma is m... Continue Reading

Anorexia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Anorexia is a type of eating disorder that is characterized by distortion of body image, intense fear of gaining weight, and extremely disturbed eating behaviour. Symptoms of anorexia can include low body weight, lack of menstruation among girls and women, severe food restriction, low blood pressure, brain damage, severe constipation, multi-organ failure and infertility. According to researchers, the risk factors associated with anorexia can be psychological, social, biological, behavioural, and genetic factors. ... Continue Reading

Valvular Heart Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Valvular heart disease is a condition in which heart valves does not work properly. There are four types of the valves present in the heart namely; tricuspid, mitral, pulmonary and aortic valves. Heart valves comprise of tissue flaps that open and close with each heartbeat and ensure the right direction of blood flow. Due to infections, birth defects, and age-related changes, heart valves do not function properly, with some of the problems observed in valvular heart diseases including; stenosis, regurgitation, and atresia... Continue Reading

Polycystic Ovary Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Polycystic ovary syndrome refers to an imbalance of hormone that causes mood disorders, metabolic syndrome, insulin resistance and obstructive sleep apnea. An absence of ovulation, high levels of androgens, and cyst formation in both ovaries are observed in most of the patients with polycystic ovary syndrome. The disease is also the major cause of anovulatory infertility, causing trouble in women to conceive naturally. ... Continue Reading

Angina Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Angina is a condition in which chest pain occurs when the heart muscle doesn’t get enough oxygen-rich blood. Patients having angina suffer from squeezing and pressure in the chest, and pain in the shoulder, arms, neck, and jaws. Angina is one of the symptoms of cardiovascular disease such as coronary heart disease. In coronary heart disease, plaques build up in the coronary arteries that reduce the flow of oxygen-rich blood which can cause blockage in the blood flow. Angina can be treated by aspirin, nitrates, beta-... Continue Reading

Cerebrovascular Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Cerebrovascular disease also known as stroke, is a condition caused by cerebral ischemia or haemorrhage. Ischemic events are further classified on the basis of occurrences of (in vertebrobasilar or carotid distribution) and duration of symptoms. Facial weakness, vertigo, dysphagia, diplopia, dysarthria, gait ataxia, hemisensory numbness, hemiparesis, limb dysmetria, cortical blindness, and bilateral weakness and numbness are some of the symptoms observed in the patients with ischemic stroke. Cerebrovascular disease can be... Continue Reading

Diabetes Insipidus Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Diabetes insipidus is a disorder in which kidney passes an abnormal amount of odourless and dilute urine that causes patients to drink plenty of liquids. Diabetes insipidus is categorized into four types namely; central diabetes insipidus, nephrogenic diabetes insipidus, gestational diabetes insipidus, and dispogenic diabetes insipidus. One of the major complication associated with diabetes insipidus is dehydration in which fluid intake is less than fluid loss. The symptoms of diabetes insipidus include fatigue, dry skin,... Continue Reading

Gestational Diabetes Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Gestational diabetes occurs in women, during the 24th to 28th week of pregnancy, due to insufficient secretion of insulin during pregnancy. During pregnancy, a female body undergoes many changes such as human chorionic gonadotropin hormone secretion and weight gain. Women with gestational diabetes are found to be mild thirstier than normal. ... Continue Reading

Interstitial Cystitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Interstitial cystitis, also known as painful bladder syndrome is a condition that causes painful urinary symptoms that differs from person to person. Mild discomfort, tenderness in the pelvic area, bladder pain and increased frequency to urinate, are some of the observed symptoms in the patients suffering from interstitial cystitis. Irritable bowel syndrome, chronic fatigue syndrome, fibromyalgia and autoimmune diseases are also observed to be associated with interstitial cystitis in the patients. ... Continue Reading

Osteoporosis Osteitis Deformans Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Osteoporosis osteitis deformans also known as Paget's disease of bone, is a condition that causes enlarged and weakened bones. The cause of paget’s disease is still unknown and can occur in the any bone of the body such as the spine, leg bones, skull, and pelvis and can lead to fracture, arthritis in joints and bone pain. Pressure on nerves, headache, hearing loss, increased head size, hip pain, are some of the symptoms observed in the patients with paget’s disease. ... Continue Reading

Peripheral Artery Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Peripheral artery disease is a condition in which plaque, comprising of fat, calcium, cholesterol, fibrous tissue and other substances present in the blood, build-up in arteries that supply blood to the brain, limbs and other organs. Atherosclerosis is a condition when plaques build-up in the arteries and limits the oxygen-rich blood flow to the body. Peripheral artery disease affects the leg arteries that can cause numbness and pain. In severe cases, gangrene (tissue death) can occur that can further lead to leg amputati... Continue Reading

Liposarcoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Liposarcoma is a type of tumour that arises from fat tissues in thighs, legs, abdomen, and retroperitoneum. Liposarcoma is also considered as malignant tumour because it spread to surrounding organs. According to the World Health Organization, liposarcoma is characterized into five types including, myxoid, well differentiated, dedifferentiated, round cell, and pleomorphic. Liposarcoma is generally observed as painless enlarged mass. It affects men and women equally. Well differentiated liposarcoma are non-metastasizing tu... Continue Reading

Liver Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Liver cancer is a type cancer in which malignant cells gets formed in the liver tissues. There are two types of liver cancer including hepatocellular carcinoma and intrahepatic cholangiocarcinoma (also known as bile duct cancer). Hepatocellular is a type of adenocarcinoma and the most common type of liver cancer. Liver cirrhosis or hepatitis is observed as the major risk factor for liver cancer. Liver cancer is characterized by hard lump formation (at the right side of rib cage), abdominal discomfort, pain around shoulder... Continue Reading

Liver Cirrhosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Liver cirrhosis is a condition in which liver deteriorates and gradually ceases the liver function. The healthy tissues of the liver are replaced by the scar tissues that block the blood flow in the liver. The main functions of the liver include removal of waste products, making new proteins, producing bile, and processing of the nutrients. The building up of scar tissue gets worse throughout the period and causes chronic liver failure which is also known as end stage liver disease. Chronic hepatitis C, alcoholism, non-al... Continue Reading

Lupus Nephritis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Lupus nephritis is a type of inflammation which is caused by an autoimmune disease, systemic lupus erythematosus. The body’s own cells are attacked by body’s immune system due to the formation of autoantibodies, in the case of systemic lupus erythematosus. The signs and symptoms of lupus nephritis include foamy urine, high blood pressure, and edema in legs, face, feet, and ankles. Kidney problems also occur in patients with lupus nephritis that can cause fever, muscle pain, red rashes, and joint pain. Systemic... Continue Reading

Macular Edema Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Macular edema causes the building-up of fluid in macula region of the eye. The macula is a light sensitive tissue, present at the center of the retina and is responsible for the sharp, straight headed vision. Building-up of fluid in macula region leads the vision to distort. Diabetic retinopathy (which is most common in diabetic patients) is observed as the common cause of macular edema. However, macular edema can also occur after surgery associated with age related macular degeneration or inflammatory disease of the eye.... Continue Reading

Nuclear factor-kappa B (NF-kB) Inhibitors Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Drug manufacturing companies are constantly involved in the quest to find better and new treatment strategies by targeting NF-kB which can be effective in various indications including cancer and chronic inflammation treatment. Various companies are developing drug candidates using different technologies for the development of effective and better drugs, which is driving the growth of the pipeline. ... Continue Reading

Mantle Cell Lymphoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Mantle cell lymphoma is a kind of disease that affects the lymphatic system (which is a part of immune system). Mantle cell lymphoma is life-threatening, slow-growing cancers which involves accumulation of cancerous B-cells at mantle zone in the lymph node. Mantle cell lymphoma can be symptomatized by night sweats, fever, weight loss and fatigue. Intestinal obstruction, multiple intestinal polyps, high blood count, and intussusception are observed in patients with mantle cell carcinoma. Somatic DNA damage is observed as t... Continue Reading

Measles Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Measles, also known as rubella, is caused by viral infection of measles virus that transfers through the respiratory route and causes systemic disease. Cough, fever, runny nose, rashes, and watery eyes (also known as conjunctivitis) are the symptoms observed in patients with measles. Two or three days after the occurrence of symptoms, tiny white spots (also known as kolpik spots) begins to appear in the oral cavity. Kolpik spots are flat red with small bumps. ... Continue Reading

Medulloblastoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Medulloblastoma is a type of malignant brain tumour that occurs in neuroepithelial tissue in children. Based on age, disease spread, and degree of surgical resection of the disease, medulloblastoma is stratified into standard and high-risk categories. Increased intracranial pressure and cerebellar dysfunction along with the headache, vomiting, and ataxia, are observed in patients with medulloblastoma. ... Continue Reading

Meniere’s Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Meniere's disease is a type of disorder that causes congestion in the ear, hearing loss, dizziness (also known as vertigo), and ringing in the ears (also known as tinnitus). In some cases, patients fall due to severe vertigo and such sort of attack called drop attacks. It has been observed that meniere’s disease occurs mostly between 40 to 60 years of age. Meniere's disease is caused by fluid build-up in the labyrinth which comprises of two parts, including the membranous labyrinth and bony labyrinth. ... Continue Reading

Meningioma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Meningioma is a type of cancer that affects the membranes surrounding the spinal cord and brain (also known as meninges). Meningioma is categorized into two types including, benign and malignant. Meningioma can be symptomatized by a headache, seizures, weakness in legs and arms, and vision loss. In some cases, carelessness, memory loss, and, unsteadiness, are also observed in some of the patients. Meningioma can also occur due to the mutation in neurofibromatosis gene (NF2). ... Continue Reading

Meningitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Meningitis is an inflammatory disease which is caused by infection due to bacteria, viruses, parasites, and fungi. It can also occur due to autoimmune diseases and certain medications. The infections due to bacteria first attack the upper respiratory tract and then passes to the brain through blood. Pneumococcal meningitis is caused by Streptococcus pneumonia and meningococcal meningitis occurs due to Neisseria meningitides infection.  ... Continue Reading

Merkel Cell Carcinoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Merkel cell carcinoma is a type of skin cancer that develops as painless bumps, due to sun exposure. Bumps can be red-violet coloured or skin coloured and grow rapidly surrounding lymph nodes. The risk factors associated with merkel cell carcinoma are excessive sun exposure, chronic immune suppression, merkel cell polyomavirus, and aging. The main cause of occurrence of merkel cell carcinoma is somatic mutations in DNA. ... Continue Reading

Metachromatic Leukodystrophy (MLD) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Metachromatic leukodystrophy (MLD) is an inherited disease that causes fat accumulation in cells. The disease affects the nervous system which produces myelin sheath for insulation and protection of nerves. The fatty deposition, called sulfatides in nerve cells causes the destruction of white matter, which is formed by myelin sheath. It further deteriorates the cognitive functioning of nerves such as an ability to walk, loss of sensation (also known as peripheral neuropathy), seizure, incontinence, inability to speak, par... Continue Reading

Migraine Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Migraine is a type of a severe headache that is characterized by the intense throbbing in one area of the head. According to National Institute of Neurological Disorders and Stroke, migraine is three times common in women than in men and it is heralded by visual disturbances such as zig-zag lines vision and flashing lights. People having migraine generally have frequent attacks that cause, anxiety, stress, hormonal level changes, and lack of sleep. The duration of migraine pain ranges from four hours to three days. In som... Continue Reading

Myocardial Ischemia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Myocardial ischemia is a cardiovascular disorder that causes angina, shortness of breath and cardiac arrhythmias. Myocardial ischemia is one of the reasons of the sudden cardiac death. Due to obstruction of coronary blood flow, oxygen and glucose flow is interrupted that causes impairment of cellular metabolism. In an electrocardiogram, the ST-segment depression is observed as the clinical sign of myocardial ischemia. ... Continue Reading

Nasal Polyps Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Nasal polyps are the type of lesions that arises from the mucosa of the nasal cavity. The cause of nasal polyps is still unknown. According to researchers, chronic inflammation in the nose and nasal sinuses are responsible for the occurrence of nasal polyps. Nasal polyps can be symptomatized by the runny nose, postnasal drip, absent sense of smell, facial pain, pain in upper teeth, snoring, persistent stuffiness, and sense of pressure over the forehead. The risk factors for nasal polyps include asthma, allergic fungal sin... Continue Reading

Neurofibromatosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Neurofibromatosis (NF) is an autosomal-dominant genetic disorder characterized by neurofibromas of the nerves and skin, café-au-lait spots on the skin (spots that look like coffee with milk), and developmental anomalies of the bones, muscles, and viscera. Usually there are two distinct types of NF namely; NF type 1 and NF type 2, also known as NF1 and NF2, respectively. Recently, a third type, known as schwannomatosis has been identified. ... Continue Reading

Neurofibromatoses Type I Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Neurofibromatoses type I is a genetic condition characterized by the growth of tumours along the nerves in the brain, skin and other parts of the body, and skin pigmentation. Neurofibromatoses is an autosomal dominant disorder which is caused by the mutation in NF1 gene, a tumour suppressor gene, that encodes protein to stop growing and dividing in an uncontrolled manner. ... Continue Reading

Nocturia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Nocturia is a condition that is characterized by the need of more than one times micturition per night. The disease is divided into two categories, lower urinary tract dysfunction, and upper urinary tract dysfunction. Nocturia is also considered as a symptom associated with overactive bladder and benign prostate obstruction. Nocturia generally occurs to older people (greater than 65 years of age). Certain risk factors that can cause nocturia in both men and women are caffeine, diuretics medications, excessive fluids befor... Continue Reading

Non-Alcoholic Fatty Liver Disease (NAFLD) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Non-alcoholic fatty liver disease (NAFLD) is a condition in which fat builds up in the liver. There are two types of NAFLD, simple fatty liver and non-alcoholic steatohepatitis (NASH). No complications or liver cell damage occur in patients with the simple fatty liver. NASH is associated with liver cell damage and inflammation that causes scarring or fibrosis, leading to liver cancer. The complications associated with NAFLD are liver failure, cardiovascular disease, and liver cancer. ... Continue Reading

Obesity Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Obesity, also known as adiposity, is a condition in which unhealthy amount of fat deposition occurs in the body. Obesity is characterized by an increment of amount and size of fat cells in the body. The medical professionals measure waist circumference and body mass index for diagnosis of obesity and overweight. There are many complications associated with obesity such as high blood pressure, metabolic syndrome, atherosclerosis, diabetes, heart disease, cancer, high blood cholesterol, and sleep disorders. ... Continue Reading

Obsessive-Compulsive Disorder Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Obsessive-compulsive disorder is a type of anxiety disorder in which person has compulsive behaviour and uncontrollable recurring thoughts. The signs and symptoms of obsessive-compulsive disorders are obsession and compulsion. Obsession involves aggressive and unforbidden thoughts related to sex, religion and harm, fear of germs, and having things in symmetrical order. Compulsion includes excessive cleaning, ordering things in a precise way, and repeatedly checking on things. According to the researchers, the brain circui... Continue Reading

Obstructive Sleep Apnea Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Obstructive sleep apnea is a chronic disorder that is characterized by the stop or pause breathing or shallow breathing during sleep. People with obstructive sleep apnea pause their breathing more than normal and start breathing again with loud or choking sound. Based on the frequency of pause in breathing, the amount of sleepiness, and level of oxygen in the blood, the disease can be categorized into mild, moderate and severe degrees. If left untreated, obstructive sleep apnea can lead to daytime sleepiness and also incr... Continue Reading

Ocular Hypertension Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Ocular hypertension is the increased intraocular pressure in the eyes. If left untreated, the disease can further lead to glaucoma or permanent loss of vision. Clinically, it is estimated that 21 mmHg eye pressure or greater denotes the occurrence of ocular hypertension. The excessive aqueous humour production, inadequate drainage of aqueous humour, eye trauma, and steroidal medications are some of the causes of ocular hypertension. ... Continue Reading

Onychomycosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Onychomycosis is also known as fungal nail infections, caused by yeasts, particularly Trichophyton rubrum and Trichophyton mentagrophytes. Peoples having weak immune system are more susceptible to the disease. Onychomycosis is classified into four types, distal subungual onychomycosis, proximal subungual onychomycosis, white superficial onychomycosis and candida infections of the nail. There are some risk factors associated with onychomycosis such as diabetes and peripheral artery disease, psoriasis, wearing tight shoes, ... Continue Reading

Osteonecrosis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Osteonecrosis is a condition in which degradation of bones occurs due to decrease of blood flow to bones in joints. Osteonecrosis is also known as avascular necrosis, aseptic necrosis, or ischemic necrosis. There are some risk factors associated with osteonecrosis such as alcohol use, injury to joints, increased pressure inside the bone, and steroidal medications. Some procedures such as chemotherapy, radiation therapy, and organ transplant are also found as the cause of osteonecrosis. The most common symptom associated w... Continue Reading

Ornithine-Transcarbamylase Deficiency Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Ornithine-transcarbamylase deficiency is a genetic disorder which causes the accumulation of excess ammonia in the blood. Ammonia is the residual product of metabolism of protein, which is toxic in high concentration. Lack of energy, unwilling to eat, poorly controlled body temperature or breathing rate, pyloric stenosis, splenomegaly, cerebral edema, hepatic failure, and aminoaciduria are the observed symptoms of the disease. The complications associated with ornithine-transcarbamylase deficiency are intellectual disabil... Continue Reading

Osteogenesis Imperfecta Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Osteogenesis imperfecta, also known as brittle bone disease, is a genetic disorder that causes weak bones formation. People with osteogenesis imperfecta generally have weak bones that break easily. Osteogenesis imperfecta is classified into eight categories, designated type I to type VIII. Osteogenesis imperfecta type I is the mildest form of the disease that is characterized by the bone fracture during adolescent and childhood stage. People with milder form of osteogenesis imperfecta are susceptible to hearing loss in ad... Continue Reading

Otitis Media Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Otitis media is a set of inflammatory disease that causes infection in the middle ear and is found to be common in children (around three years of age). The disease can be symptomized by sudden onset of ear pain, vomiting, severe earache, fever, and loss of hearing due to build-up of fluid. There are several risk factors for occurrence of otitis media such as, exposure of cigarette smoke, use of pacifier, and have close contact with other infected children. The complications associated with otitis media include mastoiditi... Continue Reading

Ovarian Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Ovarian Cancer is a tumour that arises from the ovaries or areas of peritoneum or fallopian tube. Ovarian cancer can be symptomized by pain or swelling in the abdomen, gastrointestinal problems such as constipation and gas, pain in the pelvis, and vaginal bleeding. There are several risk factors for occurrence of ovarian cancer such as breast cancer, uterine cancer or colon cancer, endometriosis, have never given birth, having genetic mutation in BRCA1 or BRCA2 gene and patients associated with lynch syndrome. ... Continue Reading

Pemphigus Vulgaris Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pemphigus vulgaris is an autoimmune disorder that causes blisters in the skin and mucous membranes. The disease can be symptomatized by abnormal blistering of the skin and the oral cavity, atypical scarring of the skin, urticaria, recurrent cutaneous abscess formation, weight loss, and acantholysis. Certain medications that can cause pemphigus vulgaris are chelating agents such as penicillamine, pyrazolones, non-steroidal anti-inflammatory drugs, rifampin, beta-lactam antibiotics, and angiotensin converting enzyme inhibit... Continue Reading

Periodontitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Periodontitis is a type of disease that causes infections in gums and other tissues that support the teeth. The gums pull away from the teeth and form pockets. There are several risk factors associated with periodontitis such as smoking, metabolic disease, hormonal changes in women and girls, other illness such as HIV (human acquired immunodeficiency syndrome) and cancer, and certain medications that reduces the flow of saliva. ... Continue Reading

Pertussis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pertussis, also known as whooping cough, is a respiratory disease that is caused by bacterium Bordetella pertussis. Pertussis is most common in young children and infants. The infection occurs due to the attachment of bacteria to the cilia of the upper respiratory system. The bacteria releases toxins that damage cilia and causes airways to swell. The disease spread from person to person by sneezing or coughing. Pertussis can be symptomatized by runny nose, mild cough, low grade fever, and apnea. According to the... Continue Reading

Pheochromocytoma Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pheochromocytoma is a type of benign tumour that occurs in medulla of the adrenal glands which leads to excess release of adrenaline. The tumour forms in the nerve tissue of the adrenal glands. There are two adrenal glands present on the top of each kidney. Each adrenal gland comprises of adrenal cortex and adrenal medulla. Catecholamines such as adrenaline and noradrenaline, controls blood pressure, heart rate, and blood sugar. ... Continue Reading

Pigmented Villonodular Synovitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pigmented villonodular synovitis is the noncancerous disease in which abnormal growth of tissue occurs that lines the joints and tendons. Pigmented villonodular synovitis is categorized into two types, diffuse form and local or nodular form. The disease can be symptomatized by locking of joints, limitation of movements, and pain. In some cases, degradation of joint structure is observed. The cause of the disease is still unknown. Pigmented villonodular synovitis can be diagnosed by certain imaging techniques such as magne... Continue Reading

Poliomyelitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Poliomyelitis is an infectious disease which is caused by viruses (polioviruses) that belongs to picornaviridae family. Poliomyelitis generally affects nerves and can leads to total paralysis. The disease can be symptomatized by gastroenteritis, malaise, respiratory illness, and paralysis. Poliomyelitis is classified into three categories paralytic poliomyelitis, nonparalytic poliomyelitis, and abortive poliomyelitis. Polioviruses can be spread by direct contact with the infected person, contact with infected faeces, and ... Continue Reading

Pompe Disease Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pompe Disease is a genetic disorder that is caused by building up of glycogen in body’s organs and tissues. This further leads to impairment of the ability to function normally. According to the researchers, there are three types of pompe disease, including non-classic infantile-onset, late-onset, and classic infantile-onset. The non-classic infantile-onset pompe disease is generally characterized by delayed motor skills. The classic form of infantile-onset pompe disease causes myopathy, hypotonia, and hepatomegaly.... Continue Reading

Portal Hypertension Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Portal hypertension is a disorder in which pressure in portal vein and tributaries is increased and portal pressure gradient is more than 10 mmHg. The portal pressure gradient predicts the decompensation of cirrhosis, hepatocellular carcinoma, and development of varices. The development of gastroesophageal varices, one of the consequences of portal hypertension, can cause variceal haemorrhage. ... Continue Reading

Postherpetic Neuralgia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Postherpetic neuralgia is a type of pain that occur due to nerve damage. The disease is one of the complications of shingles rash. Postherpetic neuralgia can be symptomatized by pain in the nerves, sensitive and itchy skin, muscle weakness, tremor, and paralysis. Aging, acute pain and severe rash during shingles, and lower immunity are the risk factors for developing poatherpetic neuralgia. The diagnosis of postherpetic neuralgia involves practical and accessible questionnaires. ... Continue Reading

Prader-Willi Syndrome (PWS) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Prader-willi syndrome (PWS) is a genetic disorder that causes alteration in eating, behaviour and mood, intellectual development, and physical growth. The disease occurs due to mutation in chromosome 15, which regulate the gene expression. The inability to control eating is one of the main symptoms of PWS. The physical symptoms of PWS generally prompts the occurrence of the disease in the new-born. There are few criteria that defines PWS, including extremely weak muscles, feeding difficulties, uncontrollable overeating, r... Continue Reading

Premature Ejaculation Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Premature ejaculation is a type of male sexual disorder with an intravaginal ejaculatory latency time of less than one minute. High levels of sexual anxiety and altered sensitivity of serotonin receptors are found as an evidence in most of the men with premature ejaculation. Premature ejaculation can be defined by three criteria such as lack of sexual satisfaction, short ejaculatory latency, and lack of control over ejaculation. Some of the risk factors associated with premature ejaculation are endocrinopathy, opiate with... Continue Reading

Presbyopia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations and Other Developments

Presbyopia is an age-related eye condition that causes visual impairment gradually. The disease has been described as "an irreversible optical failure, an unexplained evolutionary blunder that comes as a psychologic shock”. Though not incapacitating if corrected, presbyopia without optical correction results in an inability to perform once-effortless near tasks at a customary working distance without experiencing visual symptoms. The disease can result from the  ... Continue Reading

Pressure Ulcer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pressure ulcer is the type of ulcer that occurs due to injury in which breakdown the skin and underlying tissues. The injury occurs due to application of a constant pressure for a certain period. This causes cessation of nutrition and oxygen supply to the tissues, tissue necrosis and tissue ischemia. It has been estimated that the tissues are capable of sustaining 30-32 mmHg pressure for a small period of time. Increased pressure causes microcirculatory occlusion which further leads to tissue death and ulceration. ... Continue Reading

Acne Vulgaris Therapeutics - Pipeline Analysis, Clinical Trials & Results, Patents, Designations, Collaborations, Patient Size, Epidemiology Forecast to 2023, and Unmet Needs within the Market

Acne vulgaris develops on the face and upper trunk and most often affects adolescents. The causes of the acne include excess oil production, clogging of air follicles by oil and dead skin cells, and excess activity of androgens. The clinical presentation of acne vulgaris ranges from a mild comedonal form to severe inflammatory cystic acne of the face, chest, and back. ... Continue Reading

Acromegaly Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Acromegaly is a type of hormonal disorder that causes excessive release of growth hormone from pituitary gland in the body. Acromegaly is generally diagnosed in middle aged adults. Some of the complications associated with acromegaly are increased risk of cardiovascular disease, high blood pressure, arthritis, type 2 diabetes, and colon polyps. One of the common symptoms of acromegaly is abnormal growth of hands and feet. In addition, release of excess growth hormone is observed in noncancerous tumours of pituitary gland ... Continue Reading

Acute Back Pain Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Acute back pain is the constant and sharp pain at the back that occurs when person falls or lifts something heavy and gradually becomes worse. According to researchers, acute back pain can be caused by ruptured disks, spasms, disk breakdown, and tense muscles. Acute back pain is also associated with various diseases and conditions such as scoliosis, arthritis, pregnancy, kidney stones, endometriosis, spondylolisthesis, and infections. Acute back pain can be diagnosed by blood test, computed tomography, magnetic resonance ... Continue Reading

Common Cold Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Common cold, also known as nasopharyngitis, is a disease that is caused by viruses and is characterized by coughing, fever, sore throat, and sneezing. Common cold is generally harmless, but due to bacterial infection, it can cause a serious complication, sinuses. Sometimes, it can spread to other body parts and can cause ear infection, throat infection, and pneumonia. People having chronic pulmonary obstructive disease, are more susceptible to common cold. Common cold can spread through direct contact with an infected per... Continue Reading

Neisseria Gonorrhoeae Infections Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Neisseria gonorrhoeae infections is a sexually transmitted disease that is caused by Neisseria gonorrhoeae bacterium which cause infections in throat, rectum, and genitals. In men, the observed symptoms of gonorrhoeae infections are burning sensation during urination, painful and swollen testicles, and white, green or yellow discharge from the penis. In women, the observed symptoms of gonorrhoeae are vaginal bleeding during periods, increased vaginal discharged, and burning sensation during urination. ... Continue Reading

Melasma (Chlosma) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Melasma, also known as chlosma, is characterized by localized, chronic acquired hypermelanosis of the skin that occur due to melanogenesis dysfunction. It is characterized by the appearances of brown macules distributed symmetrically on the sun-exposed area of the body. It generally occurs due to more use of dermatological care products. The disease affects the quality of life of patient, due to frequent facial involvement. Some of the risk factor associated with the disease are pregnancy, sexual hormones, sun exposure, s... Continue Reading

Microscopic Polyangiitis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Microscopic polyangiitis is an inflammatory disorder that leads to the damage of organs such as kidneys, lungs, skin, joints, and nerves. The disease can be symptomatized by weight loss, inflammation of the kidneys, skin lesions, fever, nerve damage, skin rash, muscle and joint pain, loss of sensation, seizures, abdominal pain, and cough. However, the cause of microscopic polyangiitis is unknown, but it is thought that the overactive immune system causes the inflammation in the tissues and blood vessels. ... Continue Reading

Multiple System Atrophy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Multiple system atrophy is a type of neurodegenerative disorder that affects movement of the body and the autonomic nervous system which leads to loss of function and death of the nerve cells in spinal cord and brain. Multiple system atrophy can be symptomatized by erectile dysfunction, bladder control and fainting spells. Due to motor nervous system impairment, difficulties with speech and gait, along with tremor and rigidity occurs. However, the cause of the disease is still unknown, but it has been observed that the ac... Continue Reading

Myocarditis Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Myocarditis is an inflammatory disorder of cardiac muscles that is caused by toxic substances, immune system, infections and autoimmune disease. The infectious strains (bacteria or viruses) are generally responsible for the acute myocarditis in which subsequent disturbance of right or left ventricular function occurs. Myocarditis can be easily diagnosed by long-term electrocardiogram, computed tomography, magnetic resonance imaging, electrocardiography, and diagnostic catheterization. Myocarditis can be symptomatized by f... Continue Reading

Myotonic Dystrophy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Myotonic dystrophy is a genetic disorder that occurs due to mutation in DMPK gene and CNBP gene which affects the functioning of muscles and other body systems. People having myotonic dystrophy have progressive weakness of muscles in hands, legs, face, and neck which get worse over time. There are two types of myotonic dystrophy, myotonic dystrophy type I and myotonic dystrophy type II. Myotonic dystrophy can be diagnosed by genetic test, physical exam, and electromyography. ... Continue Reading

Pre-Eclampsia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Pre-eclampsia is a disorder of high blood pressure that causes decrease in blood supply to the growing foetus. The disease can be severe if left untreated, and can cause seizure or coma to the patient, a condition called as eclampsia. One of the complication associated with pre-eclampsia is HELLP syndrome which is characterized by low platelet count, hemolysis, and elevated liver enzymes. Some of the risk associated with pre-eclampsia that affects foetus are lack of nutrients and oxygen, preterm birth, and stillbirth. Acc... Continue Reading

OX-40 Receptor Agonist Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Drug manufacturing companies are constantly involved in the quest to find better and new treatment strategies by targeting OX-40 receptor which can be effective as anti-cancer therapies. Various companies are developing drug candidates using different technologies for the development of effective and better drugs, which is driving the growth of the pipeline. ... Continue Reading

Interleukin-6 (IL-6) Inhibitors Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Interleukin-6 inhibitors acts on the IL-6 receptor and belongs to a group of cytokine receptors that are expressed by leukocytes. IL-6 receptor plays an important role in the functioning of the immune system. It has a characteristic role in systemic inflammation in numerous disease conditions, including rheumatoid arthritis, and psoriatic arthritis.  However, with the complete knowledge of their role in pathogenesis of different diseases from inflammatory ... Continue Reading

Proteasome Inhibitors Therapeutics Pipeline, 2017 - Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Proteasome inhibitors are the drugs that block the proteasomes, a cellular component that breakdown proteins. The proteasome inhibitors are being studied in the treatment of multiple myeloma, cancer, inflammatory disorders, and autoimmune disorders. A breakthrough multiple myeloma treatment received approval 2003 for, Bortezomib, the first proteasome inhibitor, which is a reversible boronic acid inhibitor of the chymotrypsin-like activity of proteasome. ... Continue Reading

Retinitis Pigmentosa Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designations, Collaborations, and Other Developments

Retinitis pigmentosa is a group of rare genetic disorders, characterized by the breakdown and loss of cells in the retina of eye. Retinitis pigmentosa is familial, inherited in a variety of ways, including dominant, recessive, and sex-linked recessive. The symptoms of the disease include, loss of night vision, gradual loss of central and peripheral vision, and problems with color vision, difficulty in the daily activities such as reading, driving, walking, and reorganization of the faces ... Continue Reading

Hypertrophic Scars Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designations, Collaborations, and Other Developments

Hypertrophic scars occur due to the deposition of excessive amounts of collagen during the healing process of cuts, burns, and body piercings. Hypertrophic scars become raised, swollen and reddened during wound healing causing them to stand out from the surrounding skin. These scars can itch and be painful, and are uniform. Hypertrophic scar may contain nerves and blood vessels and these scars are often found on the breastbone, ears, and shoulders. Positive ... Continue Reading

Urinary Tract Infections (UTIs) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Urinary tract infections (UTIs) refer to a common bacterial infection disease, that occurs in either a community or healthcare setting. Typical symptoms of UTIs include fever, chills, malaise, flank pain, back pain, and/or costo-vertebral angle pain or tenderness, that occur in the presence of a functional or anatomical abnormality of the urinary tract or in the presence of catheterization. ... Continue Reading

Peanut Allergy Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Peanut allergy is one of the most common type of allergies caused by a legume, known as peanut. The symptoms of the disease include, hives, nausea, stomach cramps, tightness in throat, tingling sensation in or around oral cavity, and rhinorrhea. It has been observed that the patients suffering with asthma and eczema are more likely to get allergy from peanuts. In severe conditions, drop in blood pressure, fainting, swelling in throat, and blockage of airway can also occur. ... Continue Reading

Methicillin-resistant Staphylococcus aureus (MRSA) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that have become resistant to many commonly used antibiotics. While it is a treatable infection, it is a significant public health issue. S. aureus (commonly referred to as "staph") is a common type of bacteria that normally lives on the skin or in the nasal passages of healthy people. ... Continue Reading

Sarcopenia Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Sarcopenia is a disease characterized by degenerative loss of skeletal muscle mass, quality, and strength associated with aging which eventually weakens a person, making it difficult for a patient to walk or move around easily. ... Continue Reading

Hemochromatosis/Iron Overload Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Hemochromatosis or iron overload in simple terms is a disorder in which body accumulates too much iron. This may be genetic or acquired as a result of other disease or treatments such as anemia, thalassemia, liver disease, excessive iron shots or pills or blood transfusions. Genetic Hemochromatosis is the most common type of iron overload disease. ... Continue Reading

Restless Legs Syndrome (RLS) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Restless leg syndrome, also called as Willis-Ekbom disease is an uncomfortable and unpleasant sensation that causes an inhibition movement in legs and it can occur at any age. The cause of RLS is not known, but researchers suspect that genes play roles in the occurrence of RLS. ... Continue Reading