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Pharmaceuticals Industry Insights

 

Pharmaceuticals

The players in the pharmaceutical industry include large pharmaceutical manufacturers, speciality pharmaceutical manufacturers, contract research organization and distributors. The pharmaceutical sector is experiencing some positive trends such as improving early-stage product pipelines, mainly for cancer and diabetes drugs and a plethora of new products being introduced. The industry is driven by various key drivers such as ageing population, rise in chronic diseases and rising demand for pharma products in the emerging economies. Apart from various favourable trends, the industry is also faced with various bottlenecks such as intense competition among the generic drug makers, pricing pressures and a comparatively declining level of research and development activity. In order to overcome these bottlenecks, the players in the market need to refocus on their R&D activities and value chain costs.

Research Reports

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Estrogen Receptor-Positive Breast Cancer Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

  • P&S Market Research Estrogen Receptor Positive Breast Cancer Pipeline Analysis report
  • Estrogen Receptor-Positive (ER+) breast cancer is the most common type of breast cancer diagnosed and it refers to the cancer cells that have receptors on their surface to bind with estrogen. Breast cancer is said to be estrogen receptor-positive (ER+), if it contains estrogen that receives signals from estrogen to promote cell growth. Breast cancer is a syndrome that affects breast tissues and cells in the breast grow in an uncontrollable manner forming ...Continue Reading

March 2017

$3250

Rhinovirus Infection Therapeutics – Clinical Pipeline Development Analysis

  • P&S Market Research Rhinovirus Infection Therapeutics Pipeline Analysis report
  • Rhinovirus is a small, non-enveloped, icosahedral virus having size of around 27 nm diameter. It contains one positive-strand RNA and belongs to Picornavirus family. Discovered in 1956, rhinovirus has over 100 antigenically distinct serotypes such as RhV A, RhV B groups, and RhV A2 and RhV C subclasses, based on their sequence similarity and cell entry receptors. Human rhinovirus is a positive-sense RNA virus of 7.2 kb single strand, having ...Continue Reading

Upcoming Report

$5100

Serine/Threonine-Protein Kinase Inhibitors Pipeline Analysis, 2016

  • P&S Market Research Serine Threonine Protein Kinase Inhibitors Pipeline Analysis report
  • Serine/threonine-protein kinases (EC 2.7.11.1) are enzyme or protein that has hydroxyl (OH) group in the side chain. Phosphorylation in serine or threonine residues may cause changes in the function of the target protein. Those drugs/ligands that inhibit phosphorylating activity of these kinases are called serine/threonine protein kinases inhibitors. Serine/threonine kinase receptors are a family of transmembrane receptors containing intracellular ...Continue Reading

Upcoming Report

$5100

Ulcerative Colitis Pipeline Analysis, 2016

  • P&S Market Research Ulcerative Colitis Pipeline Analysis report
  • The ulcerative colitis pipeline has more than 45 drugs. In pipeline analysis, drugs are analyzed based on route of administration and molecule type. The pipeline is also analyzed based on monotherapy and combination therapy, and different clinical phases including Phase III, Phase II, phase I and Preclinical stage. ...Continue Reading

Upcoming Report

$5100

Vasomotor Symptoms of Menopause Therapeutics Pipeline Analysis, 2016

  • P&S Market Research Vasomotor Symptoms of Menopause Therapeutics Pipeline Analysis report
  • Vasomotor symptoms occur when a woman reach the state of menopause and ovaries stop producing eggs, and there is a reduction in secretion of hormones such as estrogen and progesterone. It usually occurs naturally, most often between age of 45 years to 51 years. The women feel perimenopausal transition that generally occurs prior to cessation of menstruation. During perimenopausal transition, the menstruation cycle becomes ...Continue Reading

Upcoming Report

$5100

Janus Kinase (JAK) Inhibitors Pipeline Analysis, 2016

  • P&S Market Research Janus Kinase Inhibitors Pipeline Analysis report
  • Janus kinase (JAK) inhibitors block Janus kinase activator enzymes and interrupt signaling pathway. It plays an important role in host defense, oncology, autoimmunity and hematological cancers, which makes them an important target for therapeutics. Many signal transduction pathways are done by JAK activity for the normal signaling. The abnormal aberration in JAKs activity can lead to diseased state. For instance, over activation of JAK can lead to ...Continue Reading

Upcoming Report

$5100

Lysosomal Storage Disorders Pipeline Analysis, 2016

  • P&S Market Research Lysosomal Storage Disorders Pipeline Analysis report
  • The deficiency of lysosomal enzymes cause lysosomal storage disorders (LSDs). It occurs due to mutations of genes that encode proteins, enzyme and related cofactors. There are approximately 50 types of LSDs. LSDs such as Gaucher disease, Fabry disease, Niemann-Pick disease, Pompe disease, Hunter syndrome, Mucopolysaccharidosis type III, Metachromatic leukodystrophy, Tay-Sachs disease and Batten disease affect different parts of body ...Continue Reading

Upcoming Report

$5100

Phosphoinositide 3-Kinase Inhibitor (PI3K Inhibitor) Pipeline Analysis, 2016

  • P&S Market Research Phosphoinositide 3 Kinase Inhibitor Pipeline Analysis report
  • Phosphoinositide 3-kinase (PI3K) pathway regulates a number of processes such as cell growth, metabolism, survival, cell migration, protein synthesis, metabolism and proliferation. It also plays a critical role in human malignancy. Overexpressed and aberrantly activated PI3K leads to many human diseases including cancer, inflammation, and cardiovascular disease. PI3K inhibitor inhibits the action of aberrantly activated PI3K. PI3K are lipid kinase ...Continue Reading

Upcoming Report

$5100

Fungal Infections Pipeline Analysis, 2016

  • P&S Market Research Fungal Infections Pipeline Analysis report
  • Fungal Infection is a major cause of morbidity worldwide. Fungal Infections are caused by different fungi found in environment. Although, some fungi are not dangerous at all but few types of fungi are harmful to health. It involves the invasion of tissue such as skin and lung by specific type of fungi. According to Centers for Disease Control and Prevention (CDC), a public health institute in the U.S., approximately 1.5 million different species of fungi are present on ...Continue Reading

Upcoming Report

$5100

Hepcidin antagonist, Pipeline Analysis, 2016

  • P&S Market Research Hepcidin antagonist Pipeline Analysis report
  • Hepcidin is a small peptide which acts as iron regulatory hormone. The name ‘hepcidin’ is taken from the place of synthesis in hepatocytes (hep), whereas cidin denotes its antimicrobial activity. Liver is the key organ that secrete hepcidin and regulates iron hormone. Hepcidin was initially observed in human urine sample and in human blood ultrafiltrate as a small bactericidal peptide (defensin and cathelicidin) and now it is known as liver–expressed ...Continue Reading

Upcoming Report

$5100

Interstitial Cystitis (IC) Disease Pipeline Analysis

  • P&S Market Research Interstitial Cystitis Disease Pipeline Analysis report
  • Interstitial Cystitis (IC) is a painful bladder syndrome in which inflamed and irritated bladder cause recurring discomfort or pain. The symptoms of IC include an urgent or frequent need to urinate and pain during bladder filling. Women are more prone to develop this condition. Pain may be mild or so severe as to be debilitating and it can vary from day to day. IC is categorized into non-ulcerative and ulcerative. Non-ulcerative IC is the most common condition found in ...Continue Reading

Upcoming Report

$5100

Beta-Secretase (BACE) Inhibitors Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

  • P&S Market Research Beta Secretase Inhibitors Pipeline Analysis report
  • BACE is a cleaving enzyme of aspartyl protease with beta-secretase activity. It acts as a precursor of beta-amyloid (Aβ) protein. In Alzheimer’s disease, the Aβ protein fragments get accumulated in plaques in the brain. BACE initiates Aβ production by cleaving amyloid precursor protein (APP) to generate APPβ and C99, which is critical for the subsequent cleavage of C99 by gamma-secretase to release Aβ1-40 and Aβ1-42. Inhibition of BACE enzyme disrupts the ...Continue Reading

February 2017

$1750

AKT/Protein Kinase B (PKB) Inhibitors Pipeline Analysis, 2016

  • P&S Market Research AKT Protein Kinase B Inhibitors Pipeline Analysis report
  • AKT, also known as Protein Kinase B (PKB), is overexpressed or activated in large number of human cancers, including breast, lung, gastric, ovary and pancreas. AKT inhibitor inhibits the activated form of AKT that leads to normal functioning of AKT kinases. AKT has three isoforms; AKT1, AKT2 and AKT3, which play an important role in regulation of diverse cellular functions such as metabolism, motility, cell survival, cell-cycle progression and transcription. ...Continue Reading

Upcoming Report

$5100

Global BET Inhibitors Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

  • P&S Market Research BET Inhibitors Pipeline Analysis report
  • Bromodomain and extra-terminal (BET) inhibitors are small molecule inhibitors including bromodomain 2 (BRD2), bromodomain 3 (BRD3), bromodomain 4 (BRD4) and bromodomain testis (BRDT), which have anti-proliferating properties. These targets of inhibitors are supposed to bind with myc gene, which is a most desired target for cancer therapeutics. BET inhibitors are first-in-class targeted therapies that directly target bromodomain proteins to deliver a new ...Continue Reading

February 2017

$2500

Global Idiopathic Pulmonary Fibrosis (IPF) Pipeline Analysis, 2016 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

  • P&S Market Research Idiopathic Pulmonary Fibrosis Therapeutics Market report
  • Idiopathic pulmonary fibrosis (IPF) is referred to as progressive and chronic interstitial pneumonia without known cause. Pulmonary fibrosis is a disease in which tissue profound in lungs becomes stiff and dense over time. The scar tissue formation is known as fibrosis. As the fibrosis progresses and tissue become darker, lungs can't properly move oxygen into the bloodstream, which result in oxygen deficiency in brain and other organs. ...Continue Reading

February 2017

$3250

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