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Protein Expression Market

P&S Market Research-Protein Expression Market report

Protein Expression Market by System Type (Prokaryotic Expression Systems, Mammalian Cell Expression Systems, Insect Cell Expression Systems, Yeast Expression Systems, Cell-Free Expression Systems, Algal-Based Expression Systems), by Product & Services (Reagents, Expression Vectors, Competent Cells, Instruments, Service), by Application (Therapeutic Applications, Industrial Applications, Research Applications), by End User (Pharmaceutical and Biotechnology Companies, Academic Research Institutes, Contract Research Organizations) – Global Market Size, Share, Development, Growth and Demand Forecast, 2013-2023

Delivery : 24-72 Working Hours
Report Code: LS11116
Available Format: pdf
Category : Biotechnology

Protein Expression Market Overview

Protein expression refers to a method by which proteins are synthesized, altered and regulated in living organisms. In protein research, protein expression applies to either the object under study or the laboratory techniques that are required to manufacture proteins. Protein expression is an important part of proteomics study that allows the expression of recombinant proteins in various host systems. Proteins are synthesized and regulated depending upon the need in the host system. Increasing opportunities in proteomics field and the rising research activities in the global pharmaceutical industry are driving the growth of the global protein expression market. Generally, protein expression includes three processes namely; translation, transcription and post-translational modification. Moreover, there are three types of recombinant protein expression methods, such as in-vivo protein expression, in-vitro protein expression and chemical protein synthesis. Biotechnology based organizations mostly rely on protein expression for developing novel therapeutics with minimal side effects. There are various types of protein expression systems that are used for the production of a broad range of therapeutic proteins, such as interferons, interleukins and insulins.

On the basis of system type, the protein expression market is segmented into prokaryotic expression systems, mammalian cell expression systems, insect cell expression systems, yeast expression systems, cell-free expression systems and algal-based expression systems. The prokaryotic expression systems segment is expected to account for the largest share of the market in 2017. The growth in the segment is primarily attributed to the high use of prokaryotic protein expression systems, since they are cheaper as compared to other expression systems.

Based on product and services, the market is categorized into reagents, expression vectors, competent cells, instruments and services. Reagents are expected to hold the largest market share of the protein expression market during the period 2017-2023. This is majorly due to the increasing research in the expression of protein and the large-scale production of antibodies and vaccines for treatment of diseases. The services category is expected to witness the fastest growth during the forecast period due to rising trend of services for custom optimization of protein expression. Additionally, the service providers in the market are equipped with advanced products and research specialists, which is expected to drive the demand for protein expression services by, manufacturers and research laboratories.

On the basis of application, the protein expression market is segmented into therapeutic, industrial and research applications. The therapeutic application segment is expected to account for the largest share of the market in 2017, due to increasing prevalence of chronic diseases such as cancer and diabetes, globally.

End users of protein expression market include pharmaceutical and biotechnology companies, academic research institutes, contract research organizations and other users (primarily including; detergent manufacturers, leather industry, food processing industry, dairy industry, chemical industry, paper industry, bioplastic industry, breweries and cosmeceutical industry). The biotechnology and pharmaceutical companies are expected to occupy the largest share of the market during the forecast period (2017-2023), mainly due to the rising production of recombinant therapeutic proteins for disease treatment, and technological advancement in protein expression research assisted with the development of new drugs and biologics.

Protein Expression Market Dynamics

Growth Drivers and Restraints

The rising protein biologics market, increasing prevalence of chronic diseases, growth in the aging population, increase in life sciences and biopharmaceutical industries, availability of funding for protein-based research and technological advancements are key drivers for the growth of protein expression market. Sales drop in the pharmaceutical industry due to current patent expiries of major drugs, have induced intense research and development of novel pharmaceuticals in various categories. This has in turn increased the demand for more proteins in this market, hence contributing towards the growth of the market.

According to the World Health Organization (WHO), chronic diseases is a leading cause of mortality in the world, comprising of 60% of all deaths. Among all the chronic diseases, cardiovascular diseases are the leading cause of deaths globally, as per the reports of WHO. Also, approximately 17.7 million people died from cardiovascular diseases in 2015, representing 31% of all the global deaths. Of these deaths, an approximate of 7.4 million deaths were due to coronary heart disease and 6.7 million were due to stroke. In 2015, WHO also reported that, 8.8 million people died from cancer, globally, which is 1 in 6 of all the global deaths.

Cost and expense cuttings in various R&D activities in the fields of biotechnology and pharmaceutical industry, collaborations and partnerships in the market, high cost of protein expression reagents and instruments are some of the restraints hindering the growth of the protein expression market.

Opportunity and Trends

Emergence of microfluidics and untapped market in various emerging economies offer ample opportunities to the players in the protein expression market.

Protein Expression Insights by Geography

Globally, North America holds the largest market share followed by Europe. These regions have the largest share in the protein expression industry due to factors such as the presence of a well-established healthcare infrastructure and also vigorous R&D activities taking place in the region. However, Asia-Pacific is expected to witness the highest growth during the forecast period. The rising prevalence of chronic diseases in emerging countries such as China and India drives the growth of the market in Asia-Pacific.

Protein Expression Competitive Landscape

Due to extensive development in the market and high competition in the protein expression market, the companies are focusing on acquiring other players to increase their product portfolio.

In June 2017, Takara Bio Inc., submitted its Clinical Trial Notification to PMDA (Pharmaceuticals and Medical Devices Agency; Japanese regulatory agency) to conduct phase I clinical trial of oncolytic virus HF10 (Development code: TBI-1401) as regenerative medicine product in Japan. This clinical trial will be conducted in patients with advanced pancreatic cancer to evaluate safety of HF10, in combination with the existing chemotherapeutic drugs.

In February 2017, Takara Bio USA Holdings, Inc. (“TBUSH”), a part of Takara Bio Inc. completed the acquisition of WaferGen Bio-systems, Inc. (“WaferGen”). This acquisition was done to allow Takara Bio Group to augment and expand its global commercial offerings in transcriptomics, and create new market opportunities in other area of genomics.

By System Type

  • Prokaryotic expression systems
    • Escherichia coli systems
    • Other prokaryotic expression systems
  • Mammalian cell expression systems
    • Chinese hamster ovary systems
    • Other mammalian cell systems
  • Insect cell expression systems
    • Baculovirus systems
    • Other insect cell systems
  • Yeast expression systems
    • K. Lactis systems
    • Saccharomyces systems
    • Pichia systems
    • Other yeast expression systems
  • Cell-free expression systems
  • Algal-based expression systems

By Product and Services

  • Reagents 
  • Expression vectors
  • Competent cells
  • Instruments
  • Services

By Application

  • Therapeutic
  • Industrial
  • Research

By End User

  • Pharmaceutical and biotechnology companies 
  • Academic research institutes
  • Contract research organizations
  • Others

By Region

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • France
    • Italy
    • Spain
    • Rest of Europe
  • Asia-Pacific
    • China
    • India
    • Japan
    • Rest of Asia-Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle-East and Africa
    • South Africa
    • Rest of Middle East and Africa

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