Transplantation Market Size & Share Analysis - Trends, Drivers, Competitive Landscape, and Forecasts (2025 - 2032)

Transplantation Market Size

Transplantation Market Trends & Growth Drivers

3D-Printed Organs Are Key Trends

• The biggest trend in the organ transplantation market is 3D-printed organs.
• Usually, a successful transplant depends on finding a 6-out-of-6 donor, which is either found in the family itself or upon extensively searching the donor list.
• Even then, ethical concerns prevail as transplanting an organ from living people poses risks to the donor too.
• Additionally, organ procurement committees are unlikely to okay a transplant for highly aged people, those with unhealthy habits, such as smoking and heavy drinking, and those who suffer from genetic conditions that cannot be cured.
• In such cases, people often need to wait for somebody with the same blood type to die for the transplant.
• However, the deceased’s family might not always be fine with donating the organ, which can further lengthen the waiting time for patients, who may be on the verge of dying themselves.
• According to the Health Resources & Services Administration of the U.S. Department of Health & Human Services, 17 people die in the country each day waiting for a transplant.
• The usage of additive manufacturing to produce organs using the patient’s own tissue has the potential to massively reduce waiting times, decrease mortality, and improve overall outcomes.
• Dental and bone implants created via 3D printing are already in common practice, and research is now being conducted to create more vital organs via this technology, such as the heart, lungs, kidneys, and liver.
• Apar from reducing waiting times, this approach would offer cost-effective transplantation procedures that can be easily conducted at dedicated transplant centers and even ambulatory surgery centers.

Rising Incidence of Organ Failure Drives Market

• The rising number of people with chronic or acute organ failure is the strongest factor driving this market.
• Organs can stop functioning due to several reasons, including physical trauma, infection, chronic disease, genetic factors, age, and poor life habits.
• The most common among the organs prone to failure is perhaps the pancreas, with more than 500 million people suffering from diabetes around the world.
• Moreover, diabetes is also one of the biggest causes of kidney failure, forcing people into a lifetime of dialysis without a transplant.
• Similarly, as per studies, 1 in 400 people in the U.S. suffers from cirrhosis, a chronic disease that damages the liver.
• Additionally, from 6.7 million currently, the number of people in the U.S. aged 20 or more who have congested heart failure is set to reach 8.7 million by 2030.
• Due to the rising incidence of such conditions, one person enters the organ transplant waiting list in the U.S. every 8 minutes.
• Therefore, government, private, and inter-government organizations are taking steps to educate people of the importance of organ donation, either when alive or after death.
• The Organ Procurement & Transplantation Network credits these initiatives for the many records that were made in 2023 in this area, such as in the number of deceased donors, total count of transplants, and the number of liver and lung transplants performed in a single year.
• A further growth in this count not just overall but for other organs too would reflect in the rise in the demand for preservative solutions, immunosuppressant drugs, and transplantable tissues.

Research on Animal–to-Human Transplants Could Offer Business Opportunities

• Research and development for transplanting animal organs into the human body is ongoing, with a few clinical trials already taking place.
• For instance, researchers at the University of Alabama in Birmingham tested the first human preclinical model for transplanting genetically modified pig kidneys into humans.
• Similarly, researchers at the University of Maryland have performed the first emergency transplant of a genetically modified pig heart into a man, who, although survived for only two months after the procedure.
• Artificial organs for transplant surgeries are gaining momentum.
• A few of the recent advancements are smartphone-controlled hands, highly mobile modular arms, ankle–foot replacements, thought-controlled robotic legs, and retinal implants.
• This is creating opportunities for companies working in this domain to expand their business.

Transplantation Market Analysis

Product Type Analysis

Tissue products account for the largest share in 2024, with a share of 60%, and this category is expected to maintain its position in the near future. This is because of the increasing use of orthobiologics in orthopedic procedures for tissue healing, normal functioning restoration, and pain minimization, along with the rising geriatric population across the globe. Moreover, startup companies in this field are receiving investments to expand their business. For instance, in 2021, Catalyst OrthoScience, a shoulder replacement manufacturer, raised USD 12.3 million in its Series D financing round and launched the Archer R1 Reverse Shoulder System and Archer 3D Targeting Imaging Software.

Immunosuppressive drugs are set to witness the fastest growth during the forecast period. The growth in this category is ascribed to the surge in the prevalence of autoimmune disorders, such as alopecia areata, multiple sclerosis, and arthritis, combined with the rising incidence of organ failures, especially the kidneys, lungs, liver, and heart. Moreover, the surge in the disposable income in developing countries will create profitable prospects in the coming years.

The below-mentioned product types are covered in the report:

• Tissue Products (Largest Category)
• Immunosuppressive Drugs (Fastest-Growing Category)
• Preservation Solutions

Application Analysis

Tissue transplantation holds the larger revenue share, and it is likely to undergo the faster growth, with 10% CAGR, during the forecast period. The growth in tissue transplantation activities is majorly attributed to the increasing transplantation of the corneas, blood vessels, heart valves, skin, ligaments, tendons, and bones. Among these, skin grafting is the most-common tissue transplantation procedure, due to the surge in the number of burns, along with the rise in the prevalence of skin cancer and road accidents.

The report offers analysis on the following applications:

• Tissue Transplantation (Larger and Faster-Growing Category)
• Organ Transplantation

End User Analysis

Hospitals dominate the market with 55% revenue, as they are the primary centers for organ and tissue transplants. Moreover, the improving healthcare infrastructure, along with the existence of a well-defined database of donors and patients needing transplants, is fueling the revenue generation from hospitals.

Transplantation centers are projected to undergo the fastest growth during the forecast period. This growth is ascribed to the rising awareness among patients and donors about these centers, as they have specialty surgeons and other staff members to perform the procedures, along with a strong organ and tissue procurement and transplantation network. Additionally, these centers are involved in related research and development, which lead to technological as well as transplantation procedure advancements.

These end users were a part of our study:

• Hospitals (Largest Category)
• Transplant Centers (Fastest-Growing Category)
• Others

Regional Analysis

The North American transplantation market share is approximately 45%, the largest around the world in 2024. The U.S. leads the region, as it has a large patient pool for organ transplantation, especially for the kidneys, pancreas, liver, intestines, heart, and lungs. Moreover, research and development in the domain have been providing a boost to the success rate of such activities. For instance, in February 2022, Carnegie Mellon University's Department of Biomedical Engineering and Mayo Clinic signed a three-year research agreement to bioengineer innovative approaches to address the current barriers in organ transplantation.

Canada is also a significant contributor to the revenue of the North American market, owing to the high number of transplant patients in the country; however, the number of donor matches is low. To minimize this gap, the Government of Canada has announced an investment of USD 2 million for research on innovative tissue and organ donation projects. One such project involves the creation and testing of prototype technologies that employ artificial intelligence to better link organ donors with receivers. This project, being undertaken by BI Expertise of Quebec City and Ortho BioMed of Toronto, would receive USD 1 million from Health Canada till 2024.

Europe holds the second-largest share owing to the substantial number of organ donors here. Germany, the U.K., and France contribute more than half the revenue to the industry in Europe. Individually, Germany dominates the market, and it is likely to witness the fastest growth in the future, owing to the technological advancements and research and development activities in the field of bionics.

The APAC region, led by China, Japan, and India, is the third-largest market, and it is expected to be the fastest-growing in the coming years, with 11% CAGR. This will be due to a surge in medical tourism activities and increase in the incidence of chronic diseases. China accounts for the largest share, and Japan is likely to have the fastest growth during the forecast period. The reason for such a significant growth in Japan is the innovative transplant techniques that help patients’ bodies accept the transplanted organ. For instance, Kyoto University Hospital has successfully conducted the world's firs living-donor lung transplant between people of incompatible blood types using lung parts from both the patient's both parents.

The regional breakdown of the market is as follows:

• North America (Largest Regional Market)
  • U.S. (Larger Country Market)
  • Canada (Faster-Growing Country Market)
• Europe
  • Germany (Largest Country Market)
  • France
  • U.K. (Fastest-Growing Country Market)
  • Italy
  • Spain
  • Rest of Europe
• Asia-Pacific (APAC) (Fastest-Growing Regional Market)
  • China (Largest Country Market)
  • India (Fastest-Growing Country Market)
  • Japan
  • Australia
  • South Korea
  • Rest of APAC
• Latin America (LATAM)
  • Brazil (Largest Country Market)
  • Mexico (Fastest-Growing Country Market)
  • Rest of LATAM
• Middle East and Africa (MEA)
  • Saudi Arabia (Largest Country Market)
  • South Africa (Fastest-Growing Country Market)
  • Rest of MEA

Transplantation Market Share

• The transplantation market is fragmented as it includes a variety of products, including immunosuppressants, organ preservation solutions, and transplantable tissue.
• Due to the highly regulated nature of the healthcare industries, companies often dominate specific segments of the market, but not all.
• This is because companies usually only offer one kind of product.
• The major pharmaceutical companies generally dominate immunosuppressive drug sales only, while others hold the upper hand in tissue products or organ preservation solutions.

Transplantation Market Company News

• In October 2024, Oncocyte signed agreements with two organ transplant centers—one each in Germany and the U.S.—to utilize its GraftAssure assay to detect signs of damage to donor tissue early after a transplant.
• In August 2024, Getinge AB announced plans to acquire Paragonix Technologies Inc., a company offering products and services for organ transplantation, for USD 477 million.
• In September 2024, eGenesis, a biotechnology company, raised funding worth USD 191 million to transplant porcine kidneys into humans.
• In March 2024, surgeons at Massachusetts General Hospital conducted a successful transplant of a kidney from a pig into a 62-year-old patient.