Skin Replacements and Substitutes Market to Generate Revenue worth $1,869.2 Million by 2030
- Published: February 2024
The global skin replacements and substitutes market size is set to be USD 1,869.2 million by 2030, witnessing 7.0% CAGR between 2024 and 2030. This will be due to the increasing number of citizens spending on appearance enhancement, rising incidence of burns, growing rate of road accidents, surging life expectancy, and escalating prevalence of skin and chronic disease. As per the WHO, nearly 1 million people in India get severe and moderate burns each year. The high disability-adjusted life-years in India are due to burns and many other causes.
Increasing Focus on Enhance Appearance of Skin
People with skin damage due to chronic diseases and other reasons are increasingly seeking remedies to enhance their appearance. Further, due to the innovations in the healthcare sector, various products are available for use as skin replacement, such as acellular substitutes; these products are cost-effective and efficient. In these products, a nylon mesh works as the dermis, and a silicon membrane works as the epidermis. It is then implanted into porcine collagen and connected by chemical bonds for attachment to the wound base.
Deep burns can destroy both layers of the skin (dermis and epidermis), exposing them to microorganisms, which can cause infections and further complications. Therefore, quick medical guidance or surgery is advised. Artificial skin, after sterilization, has the capacity to enhance the release of cytokines and growth factors for regenerating the destroyed tissue. The width, orifice, and interconnecting pores of the graft should be ideal for the regeneration of new skin.
Continued Dominance of Wound Care Clinics and Hospitals on Market
Wound care clinics and hospitals are the largest end users as they have sophisticated facilities, expert professionals, necessary medication, and the technology required for complicated burn cases. With an increasing number of people suffering from dermatological diseases, the footfall at these healthcare centers is rising. Moreover, severe wounds are caused after surgery; hence, such skin replacement procedures are often part of the overall post-operative care regimen.
Growing Opportunities in APAC
North America is dominating the market due to the advancements in the healthcare sector and a high demand for skincare. Moreover, the key market players are collaborating with hospitals, cosmetic centers, and wound care clinics to sell and advance their skin replacement and substitute products and pursuing the approval of the FDA for them. For instance, in June 2021 Mallinckrodt Pharmaceuticals received the FDA approval for a novel skin product, called StrataGraft. It can reduce the requirement for autografts if some part of the deeper skin layers and dermal elements remains intact after a thermal burn injury.
APAC is the fastest-growing market due to the increasing demand for cosmetic procedures and the high prevalence of diabetic foot ulcers and other skin issues. Between 15 and 25% of the population with diabetes mellitus would develop a DFU at some point. As per the WHO, diabetic population in China is expected to reach 150 million by 2040 from 110 million in 2016. Moreover, India registered 31 million new diabetes diagnoses in 2019–2021.
Some of the key players in the skin and replacements and substitutes market are Acelity L.P. Inc., MiMedx Group Inc., Organogenesis Inc., Vericel Corporation, FUJIFILM Cellular Dynamics Inc., Smith & Nephew plc, Integra LifeSciences Holdings Corporation, AlloSource, and MatTek Corporation.