Retinitis pigmentosa currently exhibits a growing pipeline with 38 drug candidates, P&S Intelligence
Retinitis Pigmentosa therapeutics pipeline in 2017
Retinitis pigmentosa, also known as retinitis, is a degenerative eye disease that occurs due to the progressive degeneration of the rod photoreceptor cells in the retina of eye. The study analyzed that the retinitis pigmentosa therapeutics pipeline comprises approximately 38 drug candidates in different stages of development.
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Insights on pipeline segments
Orphan drug designations from the regulatory bodies such as Food and Drug Administration (FDA), European Medicines Agency (EMA) and Ministry of Health, Labour and Welfare (MHLW) is a key driver for the development of pipeline drugs, for treating retinitis pigmentosa. Majority of the pipeline drug candidates are being developed using the intravitreal route of administration. HORAMA S.A. is in the process of developing two phase I/II, and one Pre-Clinical therapeutics for the treatment of retinitis pigmentosa.
Maximum drugs being developed as gene therapy
Many companies are increasingly emphasizing on the development of gene therapy candidates, due to their positive clinical results in the treatment of retinitis pigmentosa. Based on molecule type, around 50.0% of the drug candidates in the retinitis pigmentosa pipeline are expected to be developed based on gene therapy.
Technological advancements spurring the growth of the retinitis pigmentosa therapeutics pipeline
Technological advancements are spurring the pipeline growth, for instance, AAV vector manufacturing platform was used in the development of AGTC-501 by the Applied Genetic Technologies Corp for the treatment of retinitis pigmentosa
Some of the key players developing drugs for the treatment of retinitis pigmentosa include jCyte, Inc., Dompe Farmaceutici SpA, ProRetina Therapeutics, S.L., and Recursion Pharmaceuticals Inc.
Retinitis Pigmentosa Therapeutics Pipeline Analysis